ENSG00000197471


Homo sapiens

Features
Gene ID: ENSG00000197471
  
Biological name :SPN
  
Synonyms : P16150 / sialophorin / SPN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 29662979
Gene end: 29670876
  
Corresponding Affymetrix probe sets: 1568964_x_at (Human Genome U133 Plus 2.0 Array)   206056_x_at (Human Genome U133 Plus 2.0 Array)   206057_x_at (Human Genome U133 Plus 2.0 Array)   216980_s_at (Human Genome U133 Plus 2.0 Array)   216981_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378787
Ensembl peptide - ENSP00000353238
Ensembl peptide - ENSP00000455266
Ensembl peptide - ENSP00000412907
NCBI entrez gene - 105369247     See in Manteia.
NCBI entrez gene - 6693     See in Manteia.
OMIM - 182160
RefSeq - XM_016999604
RefSeq - NM_001030288
RefSeq - NM_003123
RefSeq Peptide - NP_001025459
RefSeq Peptide - NP_003114
swissprot - C9JUK7
swissprot - A0A024R629
swissprot - P16150
Ensembl - ENSG00000197471
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SpnENSMUSG00000051457Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002296 T-helper 1 cell lineage commitment IDA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007162 negative regulation of cell adhesion TAS
 biological_processGO:0007163 establishment or maintenance of cell polarity TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0032609 interferon-gamma production IDA
 biological_processGO:0042130 negative regulation of T cell proliferation ISS
 biological_processGO:0042535 positive regulation of tumor necrosis factor biosynthetic process IDA
 biological_processGO:0042742 defense response to bacterium IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0050901 leukocyte tethering or rolling ISS
 biological_processGO:2000404 regulation of T cell migration ISS
 biological_processGO:2000406 positive regulation of T cell migration ISS
 cellular_componentGO:0001931 uropod ISS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005902 microvillus ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0030544 Hsp70 protein binding IPI
 molecular_functionGO:0031072 heat shock protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Basigin interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090863 GLG1 / Q92896 / golgi glycoprotein 1  / reaction / complex
 ENSG00000110876 Q14242 / SELPLG / selectin P ligand  / complex / reaction
 ENSG00000026508 CD44 / P16070 / CD44 molecule (Indian blood group)  / reaction / complex
 ENSG00000172270 BSG / P35613 / basigin (Ok blood group)  / complex / reaction
 ENSG00000007908 SELE / P16581 / selectin E  / complex / reaction
 ENSG00000197471 SPN / P16150 / sialophorin  / reaction / complex






 

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