ENSG00000172270


Homo sapiens

Features
Gene ID: ENSG00000172270
  
Biological name :BSG
  
Synonyms : basigin (Ok blood group) / BSG / P35613
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 571277
Gene end: 583493
  
Corresponding Affymetrix probe sets: 208677_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478958
Ensembl peptide - ENSP00000473664
Ensembl peptide - ENSP00000484624
Ensembl peptide - ENSP00000495088
Ensembl peptide - ENSP00000484849
Ensembl peptide - ENSP00000333769
Ensembl peptide - ENSP00000343809
Ensembl peptide - ENSP00000344707
Ensembl peptide - ENSP00000458665
Ensembl peptide - ENSP00000473393
Ensembl peptide - ENSP00000473528
NCBI entrez gene - 682     See in Manteia.
OMIM - 109480
RefSeq - XM_017027173
RefSeq - NM_001322243
RefSeq - NM_001728
RefSeq - NM_198589
RefSeq - NM_198590
RefSeq - NM_198591
RefSeq Peptide - NP_001309172
RefSeq Peptide - NP_001719
RefSeq Peptide - NP_940991
RefSeq Peptide - NP_940992
RefSeq Peptide - NP_940993
swissprot - I3L192
swissprot - P35613
swissprot - R4GMX5
swissprot - Q54A51
swissprot - R4GN83
swissprot - A0A087WUV8
swissprot - A0A087X2B5
swissprot - A0A087X215
Ensembl - ENSG00000172270
  
Related genetic diseases (OMIM): 111380 - [Blood group, OK], 111380
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bsgENSDARG00000019881Danio rerio
 BSGENSGALG00000001328Gallus gallus
 BsgENSMUSG00000023175Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPTN / Q9Y639 / neuroplastinENSG0000015664241
EMB / Q6PCB8 / embiginENSG0000017057116


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR009151  Basigin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007566 embryo implantation IEA
 biological_processGO:0015718 monocarboxylic acid transport IEA
 biological_processGO:0022617 extracellular matrix disassembly TAS
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0046689 response to mercury ion IEA
 biological_processGO:0046697 decidualization IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005739 mitochondrion HDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005537 mannose binding IEA
 molecular_functionGO:0008028 monocarboxylic acid transmembrane transporter activity TAS
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Basigin interactions
Integrin cell surface interactions
Proton-coupled monocarboxylate transport
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000005884 ITGA3 / P26006 / integrin subunit alpha 3  / complex / reaction
 ENSG00000129244 ATP1B2 / P14415 / ATPase Na+/K+ transporting subunit beta 2  / reaction / complex
 ENSG00000091409 ITGA6 / P23229 / integrin subunit alpha 6  / reaction / complex
 ENSG00000069849 ATP1B3 / P54709 / ATPase Na+/K+ transporting subunit beta 3  / reaction / complex
 ENSG00000150093 ITGB1 / P05556 / integrin subunit beta 1  / complex / reaction
 ENSG00000197471 SPN / P16150 / sialophorin  / complex / reaction
 ENSG00000100023 PPIL2 / Q13356 / peptidylprolyl isomerase like 2  / complex / reaction
 ENSG00000100156 O95907 / SLC16A8 / solute carrier family 16 member 8  / reaction / complex
 ENSG00000196611 MMP1 / P03956 / matrix metallopeptidase 1  / reaction / complex
 ENSG00000172270 BSG / P35613 / basigin (Ok blood group)  / complex / reaction
 ENSG00000141526 O15427 / SLC16A3 / solute carrier family 16 member 3  / complex / reaction
 ENSG00000155380 P53985 / SLC16A1 / solute carrier family 16 member 1  / reaction / complex
 ENSG00000105974 CAV1 / Q03135 / caveolin 1  / complex / reaction
 ENSG00000198910 L1CAM / P32004 / L1 cell adhesion molecule  / reaction / complex
 ENSG00000196262 PPIA / P62937 / peptidylprolyl isomerase A  / complex / reaction
 ENSG00000105695 MAG / P20916 / myelin associated glycoprotein  / reaction / complex
 ENSG00000143153 ATP1B1 / P05026 / ATPase Na+/K+ transporting subunit beta 1  / complex / reaction






 

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