ENSG00000100156


Homo sapiens

Features
Gene ID: ENSG00000100156
  
Biological name :SLC16A8
  
Synonyms : O95907 / SLC16A8 / solute carrier family 16 member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 38078134
Gene end: 38084093
  
Corresponding Affymetrix probe sets: 220455_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321735
Ensembl peptide - ENSP00000409547
NCBI entrez gene - 23539     See in Manteia.
OMIM - 610409
RefSeq - NM_013356
RefSeq - XM_017028685
RefSeq Peptide - NP_037488
swissprot - B0QYL4
swissprot - O95907
Ensembl - ENSG00000100156
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc16a8ENSDARG00000045153Danio rerio
 SLC16A8ENSGALG00000036897Gallus gallus
 O35308ENSMUSG00000032988Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15427 / SLC16A3 / solute carrier family 16 member 3ENSG0000014152652
O60669 / SLC16A7 / solute carrier family 16 member 7ENSG0000011859640
P53985 / SLC16A1 / solute carrier family 16 member 1ENSG0000015538037
O15375 / SLC16A5 / solute carrier family 16 member 5ENSG0000017019034
Q8NCK7 / SLC16A11 / solute carrier family 16 member 11ENSG0000017432631
SLC16A12 / solute carrier family 16 member 12ENSG0000015277930
Q7RTY0 / SLC16A13 / solute carrier family 16 member 13ENSG0000017432729
O15403 / SLC16A6 / solute carrier family 16 member 6ENSG0000010893226


Protein motifs (from Interpro)
Interpro ID Name
 IPR004743  Monocarboxylate transporter
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR030759  Monocarboxylate transporter 3
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process TAS
 biological_processGO:0015718 monocarboxylic acid transport IEA
 biological_processGO:0015727 lactate transport TAS
 biological_processGO:0035873 lactate transmembrane transport IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008028 monocarboxylic acid transmembrane transporter activity IEA
 molecular_functionGO:0015129 lactate transmembrane transporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Basigin interactions
Proton-coupled monocarboxylate transport
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172270 BSG / P35613 / basigin (Ok blood group)  / complex / reaction
 ENSG00000100156 O95907 / SLC16A8 / solute carrier family 16 member 8  / reaction / complex
 ENSG00000155380 P53985 / SLC16A1 / solute carrier family 16 member 1  / reaction
 ENSG00000141526 O15427 / SLC16A3 / solute carrier family 16 member 3  / reaction






 

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contact: otassy@igbmc.fr