ENSMUSG00000032988


Mus musculus

Features
Gene ID: ENSMUSG00000032988
  
Biological name :Slc16a8
  
Synonyms : O35308 / Slc16a8 / solute carrier family 16 (monocarboxylic acid transporters), member 8
  
Possible biological names infered from orthology : O95907 / solute carrier family 16 member 8
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 79251014
Gene end: 79254761
  
Corresponding Affymetrix probe sets: 10430467 (MoGene1.0st)   1420445_at (Mouse Genome 430 2.0 Array)   1457014_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040522
NCBI entrez gene - 57274     See in Manteia.
MGI - MGI:1929519
RefSeq - XM_017316713
RefSeq - NM_020516
RefSeq Peptide - NP_065262
swissprot - O35308
swissprot - Q5UB50
Ensembl - ENSMUSG00000032988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc16a8ENSDARG00000045153Danio rerio
 SLC16A8ENSGALG00000036897Gallus gallus
 O95907ENSG00000100156Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P57787 / Slc16a3 / solute carrier family 16 (monocarboxylic acid transporters), member 3 / O15427* / solute carrier family 16 member 3*ENSMUSG0000002516153
O70451 / Slc16a7 / solute carrier family 16 (monocarboxylic acid transporters), member 7 / O60669* / solute carrier family 16 member 7*ENSMUSG0000002010238
P53986 / Slc16a1 / solute carrier family 16 (monocarboxylic acid transporters), member 1 / P53985* / solute carrier family 16 member 1*ENSMUSG0000003290238
G5E8K6 / Slc16a5 / solute carrier family 16 (monocarboxylic acid transporters), member 5 / O15375* / solute carrier family 16 member 5*ENSMUSG0000004577537
Q8BGC3 / Slc16a12 / solute carrier family 16 (monocarboxylic acid transporters), member 12 / solute carrier family 16 member 12*ENSMUSG0000000937831
Q5NC32 / Slc16a11 / solute carrier family 16 (monocarboxylic acid transporters), member 11 / Q8NCK7* / solute carrier family 16 member 11*ENSMUSG0000004093829
Q8CE94 / Slc16a13 / solute carrier family 16 (monocarboxylic acid transporters), member 13 / Q7RTY0* / solute carrier family 16 member 13*ENSMUSG0000004436728
B1AT66 / Slc16a6 / solute carrier family 16 (monocarboxylic acid transporters), member 6 / O15403* / solute carrier family 16 member 6*ENSMUSG0000004192026


Protein motifs (from Interpro)
Interpro ID Name
 IPR004743  Monocarboxylate transporter
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR030759  Monocarboxylate transporter 3
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015718 monocarboxylic acid transport IEA
 biological_processGO:0035873 lactate transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0008028 monocarboxylic acid transmembrane transporter activity IBA
 molecular_functionGO:0015129 lactate transmembrane transporter activity ISO
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Basigin interactions
Proton-coupled monocarboxylate transport
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Il10tm1Cgn/Il10tm1Cgn,Rps6ka4tm1Jsca/Rps6ka4tm1Jsca,Rps6ka5tm1Jsca/Rps6ka5tm1Jsca
Genetic Background: B6.Cg-Il10tm1Cgn Rps6ka5tm1Jsca Rps6ka4tm1Jsca

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032988 O35308 / Slc16a8 / solute carrier family 16 (monocarboxylic acid transporters), member 8 / O95907* / solute carrier family 16 member 8*  / reaction / complex
 ENSMUSG00000025161 P57787 / Slc16a3 / solute carrier family 16 (monocarboxylic acid transporters), member 3 / O15427* / solute carrier family 16 member 3*  / reaction
 ENSMUSG00000023175 Bsg / P18572 / Basigin / P35613* / basigin (Ok blood group)*  / complex / reaction
 ENSMUSG00000032902 P53986 / Slc16a1 / solute carrier family 16 (monocarboxylic acid transporters), member 1 / P53985* / solute carrier family 16 member 1*  / reaction






 

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