ENSG00000069849


Homo sapiens

Features
Gene ID: ENSG00000069849
  
Biological name :ATP1B3
  
Synonyms : ATP1B3 / ATPase Na+/K+ transporting subunit beta 3 / P54709
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q23
Gene start: 141876124
Gene end: 141926514
  
Corresponding Affymetrix probe sets: 208836_at (Human Genome U133 Plus 2.0 Array)   226570_at (Human Genome U133 Plus 2.0 Array)   229709_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417608
Ensembl peptide - ENSP00000419962
Ensembl peptide - ENSP00000418952
Ensembl peptide - ENSP00000418353
Ensembl peptide - ENSP00000418280
Ensembl peptide - ENSP00000286371
Ensembl peptide - ENSP00000417522
NCBI entrez gene - 483     See in Manteia.
OMIM - 601867
RefSeq - NM_001679
RefSeq Peptide - NP_001670
swissprot - F8WBY4
swissprot - H7C4L9
swissprot - H7C547
swissprot - C9JXZ1
swissprot - P54709
swissprot - C9JA36
swissprot - C9J6S2
Ensembl - ENSG00000069849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp1b3aENSDARG00000015790Danio rerio
 atp1b3bENSDARG00000042837Danio rerio
 ATP1B3ENSGALG00000002764Gallus gallus
 Atp1b3ENSMUSG00000032412Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP1B2 / P14415 / ATPase Na+/K+ transporting subunit beta 2ENSG0000012924446
ATP1B1 / P05026 / ATPase Na+/K+ transporting subunit beta 1ENSG0000014315337
ATP1B4 / Q9UN42 / ATPase Na+/K+ transporting family member beta 4ENSG0000010189235
ATP4B / P51164 / ATPase H+/K+ transporting beta subunitENSG0000018600934


Protein motifs (from Interpro)
Interpro ID Name
 IPR000402  Sodium/potassium-transporting ATPase subunit beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006883 cellular sodium ion homeostasis IDA
 biological_processGO:0010107 potassium ion import IDA
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient IEA
 biological_processGO:0030001 metal ion transport IEA
 biological_processGO:0030007 cellular potassium ion homeostasis IDA
 biological_processGO:0032781 positive regulation of ATPase activity IDA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0036376 sodium ion export across plasma membrane IDA
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:0086009 membrane repolarization IDA
 biological_processGO:1901018 positive regulation of potassium ion transmembrane transporter activity IDA
 biological_processGO:1903278 positive regulation of sodium ion export across plasma membrane IDA
 biological_processGO:1903288 positive regulation of potassium ion import IDA
 biological_processGO:1903779 regulation of cardiac conduction TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005890 sodium:potassium-exchanging ATPase complex IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001671 ATPase activator activity IDA
 molecular_functionGO:0005391 sodium:potassium-exchanging ATPase activity IEA
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
Basigin interactions
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129244 ATP1B2 / P14415 / ATPase Na+/K+ transporting subunit beta 2  / complex
 ENSG00000143153 ATP1B1 / P05026 / ATPase Na+/K+ transporting subunit beta 1  / complex
 ENSG00000172270 BSG / P35613 / basigin (Ok blood group)  / reaction / complex
 ENSG00000105409 ATP1A3 / P13637 / ATPase Na+/K+ transporting subunit alpha 3  / complex
 ENSG00000163399 ATP1A1 / P05023 / ATPase Na+/K+ transporting subunit alpha 1  / complex
 ENSG00000018625 ATP1A2 / P50993 / ATPase Na+/K+ transporting subunit alpha 2  / complex
 ENSG00000132681 ATP1A4 / Q13733 / ATPase Na+/K+ transporting subunit alpha 4  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr