ENSG00000100023


Homo sapiens

Features
Gene ID: ENSG00000100023
  
Biological name :PPIL2
  
Synonyms : peptidylprolyl isomerase like 2 / PPIL2 / Q13356
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q11.21
Gene start: 21666009
Gene end: 21700015
  
Corresponding Affymetrix probe sets: 206063_x_at (Human Genome U133 Plus 2.0 Array)   206064_s_at (Human Genome U133 Plus 2.0 Array)   209299_x_at (Human Genome U133 Plus 2.0 Array)   214986_x_at (Human Genome U133 Plus 2.0 Array)   217407_x_at (Human Genome U133 Plus 2.0 Array)   223999_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395181
Ensembl peptide - ENSP00000384299
Ensembl peptide - ENSP00000406745
Ensembl peptide - ENSP00000486725
Ensembl peptide - ENSP00000334553
Ensembl peptide - ENSP00000381812
NCBI entrez gene - 23759     See in Manteia.
OMIM - 607588
RefSeq - XM_011530051
RefSeq - XM_011530041
RefSeq - XM_011530042
RefSeq - XM_011530043
RefSeq - XM_011530044
RefSeq - XM_011530046
RefSeq - XM_011530047
RefSeq - XM_011530049
RefSeq - XM_011530050
RefSeq - NM_001317996
RefSeq - NM_014337
RefSeq - NM_148175
RefSeq - NM_148176
RefSeq - XM_005261448
RefSeq Peptide - NP_680480
RefSeq Peptide - NP_680481
RefSeq Peptide - NP_001304925
RefSeq Peptide - NP_055152
swissprot - Q13356
swissprot - F8WC56
swissprot - C9JDF0
swissprot - A0A024R1C1
Ensembl - ENSG00000100023
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppil2ENSDARG00000002016Danio rerio
 PPIL2ENSGALG00000042052Gallus gallus
 Ppil2ENSMUSG00000022771Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPWD1 / Q96BP3 / peptidylprolyl isomerase domain and WD repeat containing 1ENSG0000011359325
CWC27 / Q6UX04 / CWC27 spliceosome associated protein homologENSG0000015301517
PPIL6 / Q8IXY8 / peptidylprolyl isomerase like 6ENSG0000018525015
PPIL4 / Q8WUA2 / peptidylprolyl isomerase like 4ENSG0000013101315
PPIC / P45877 / peptidylprolyl isomerase CENSG0000016893815
PPIL1 / Q9Y3C6 / peptidylprolyl isomerase like 1ENSG0000013716814
PPIB / P23284 / peptidylprolyl isomerase BENSG0000016679414
PPIH / O43447 / peptidylprolyl isomerase HENSG0000017196013
PPIL3 / Q9H2H8 / peptidylprolyl isomerase like 3ENSG0000024034412


Protein motifs (from Interpro)
Interpro ID Name
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR003613  U box domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR024936  Cyclophilin-type peptidyl-prolyl cis-trans isomerase
 IPR029000  Cyclophilin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0072659 protein localization to plasma membrane IMP
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0034450 ubiquitin-ubiquitin ligase activity IDA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Basigin interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172270 BSG / P35613 / basigin (Ok blood group)  / complex / reaction






 

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