ENSG00000171960


Homo sapiens

Features
Gene ID: ENSG00000171960
  
Biological name :PPIH
  
Synonyms : O43447 / peptidylprolyl isomerase H / PPIH
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.2
Gene start: 42658425
Gene end: 42676758
  
Corresponding Affymetrix probe sets: 204228_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361630
Ensembl peptide - ENSP00000361629
Ensembl peptide - ENSP00000402836
Ensembl peptide - ENSP00000436091
Ensembl peptide - ENSP00000405493
Ensembl peptide - ENSP00000306614
NCBI entrez gene - 10465     See in Manteia.
OMIM - 606095
RefSeq - XM_017000059
RefSeq - NM_006347
RefSeq - XM_005270362
RefSeq - XM_005270366
RefSeq - XM_011540508
RefSeq - XM_017000057
RefSeq - XM_017000058
RefSeq Peptide - NP_001317439
RefSeq Peptide - NP_006338
swissprot - C9JQD4
swissprot - C9JAN8
swissprot - O43447
swissprot - A6NM32
swissprot - H0YEL5
swissprot - Q6FH36
Ensembl - ENSG00000171960
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppihENSDARG00000041530Danio rerio
 PPIHENSGALG00000004874Gallus gallus
 Gm7879ENSMUSG00000033036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPIB / P23284 / peptidylprolyl isomerase BENSG0000016679455
PPIC / P45877 / peptidylprolyl isomerase CENSG0000016893855
PPIL6 / Q8IXY8 / peptidylprolyl isomerase like 6ENSG0000018525041
PPWD1 / Q96BP3 / peptidylprolyl isomerase domain and WD repeat containing 1ENSG0000011359340
PPIL2 / Q13356 / peptidylprolyl isomerase like 2ENSG0000010002338
PPIL1 / Q9Y3C6 / peptidylprolyl isomerase like 1ENSG0000013716837
CWC27 / Q6UX04 / CWC27 spliceosome associated protein homologENSG0000015301534
PPIL4 / Q8WUA2 / peptidylprolyl isomerase like 4ENSG0000013101329
PPIL3 / Q9H2H8 / peptidylprolyl isomerase like 3ENSG0000024034429


Protein motifs (from Interpro)
Interpro ID Name
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR024936  Cyclophilin-type peptidyl-prolyl cis-trans isomerase
 IPR029000  Cyclophilin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IC
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0065003 protein-containing complex assembly TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IC
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IDA
 cellular_componentGO:0071001 U4/U6 snRNP IDA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016018 cyclosporin A binding TAS
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IDA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136875 PRPF4 / O43172 / pre-mRNA processing factor 4  / complex
 ENSG00000117360 PRPF3 / O43395 / pre-mRNA processing factor 3  / complex






 

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