ENSDARG00000079397


Danio rerio

Features
Gene ID: ENSDARG00000079397
  
Biological name :cerkl
  
Synonyms : ceramide kinase-like / cerkl
  
Possible biological names infered from orthology : Q49MI3
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 44094311
Gene end: 44289636
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098560
NCBI entrez gene - 100037318     See in Manteia.
RefSeq - NM_001089474
RefSeq Peptide - NP_001082943
swissprot - A4QNW6
ZFIN ID - ZDB-GENE-070410-38
Ensembl - ENSDARG00000079397
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CERKLENSGALG00000008910Gallus gallus
 CERKLENSG00000188452Homo sapiens
 CerklENSMUSG00000075256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:158263ENSDARG0000003726726
cerk / ceramide kinase / Q8K4Q7* / Q8TCT0*ENSDARG0000006916925
sphk2 / sphingosine kinase 2 / Q9JIA7* / Q9NRA0*ENSDARG0000006989316
agk / Q7ZW00 / acylglycerol kinase / Q53H12* / Q9ESW4* / Acylglycerol kinase, mitochondrial *ENSDARG0000000983713


Protein motifs (from Interpro)
Interpro ID Name
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042461 photoreceptor cell development IMP
 biological_processGO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IMP
 biological_processGO:2000425 regulation of apoptotic cell clearance IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens morphology , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye increased amount , abnormal
eye decreased amount , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer has extra parts of type retinal photoreceptor layer vesicle, abnormal
retinal photoreceptor layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0000152 retina retina apoptotic , abnormal
retina cell apoptotic , abnormal
retina regulation of apoptotic cell clearance process quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0001117 post-vent region post-vent region shortened , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer decreased thickness , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer absent , abnormal
photoreceptor outer segment layer decreased thickness , abnormal
Show

 ZFA:0009127 photoreceptor cell photoreceptor cell photoreceptor outer segment decreased length , abnormal
photoreceptor cell photoreceptor outer segment degenerate , abnormal
photoreceptor cell photoreceptor outer segment disorganized , abnormal
Show

 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell photoreceptor outer segment detached from eye photoreceptor cell photoreceptor inner segment, abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell decreased amount , abnormal
retinal cone cell photoreceptor outer segment decreased length , abnormal
retinal cone cell photoreceptor outer segment degenerate , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell decreased amount , abnormal
retinal rod cell photoreceptor outer segment decreased length , abnormal
retinal rod cell photoreceptor outer segment degenerate , abnormal
retinal rod cell photoreceptor disc membrane disorganized , abnormal
retinal rod cell photoreceptor outer segment disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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