ENSMUSG00000075256


Mus musculus

Features
Gene ID: ENSMUSG00000075256
  
Biological name :Cerkl
  
Synonyms : ceramide kinase-like / Cerkl
  
Possible biological names infered from orthology : Q49MI3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C3
Gene start: 79330543
Gene end: 79456785
  
Corresponding Affymetrix probe sets: 10484261 (MoGene1.0st)   1446252_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121353
Ensembl peptide - ENSMUSP00000114325
NCBI entrez gene - 228094     See in Manteia.
MGI - MGI:3037816
RefSeq - XM_017317607
RefSeq - XM_017317603
RefSeq - XM_017317604
RefSeq - XM_017317605
RefSeq - NM_001048176
RefSeq - XM_017317599
RefSeq - XM_017317600
RefSeq - XM_017317601
RefSeq - XM_017317602
RefSeq Peptide - NP_001041641
swissprot - A2AQH1
swissprot - A2AQH0
Ensembl - ENSMUSG00000075256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cerklENSDARG00000079397Danio rerio
 CERKLENSGALG00000008910Gallus gallus
 CERKLENSG00000188452Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cerk / Q8K4Q7 / Ceramide kinase / Q8TCT0*ENSMUSG0000003589128
Sphk2 / Q9JIA7 / sphingosine kinase 2 / Q9NRA0*ENSMUSG0000005734219
Agk / Q9ESW4 / Acylglycerol kinase, mitochondrial / Q53H12* / acylglycerol kinase*ENSMUSG0000002991614
Sphk1 / Q8CI15 / Sphingosine kinase 1 / Q9NYA1*ENSMUSG0000006187814


Protein motifs (from Interpro)
Interpro ID Name
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0001917 photoreceptor inner segment IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0046625 sphingolipid binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Ngftm1.1Blhe/Ngf+,Sort1tm1Tew/Sort1tm1Tew
Genetic Background: B6.Cg-Ngftm1.1Blhe Sort1tm1Tew

 MP:0030005 increased retinal apoptosis "increase in the number of cells in the retina undergoing programmed cell death" [MGI:anna]
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Allelic Composition: Ngftm1.1Blhe/Ngf+,Sort1tm1Tew/Sort1tm1Tew
Genetic Background: B6.Cg-Ngftm1.1Blhe Sort1tm1Tew

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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