ENSDARG00000088810


Danio rerio

Features
Gene ID: ENSDARG00000088810
  
Biological name :prox1b
  
Synonyms : prospero homeobox 1b / prox1b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 19930564
Gene end: 19940473
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106319
NCBI entrez gene - 564431     See in Manteia.
RefSeq - NM_001171587
RefSeq Peptide - NP_001165058
swissprot - D2DHG1
ZFIN ID - ZDB-GENE-050107-3
Ensembl - ENSDARG00000088810
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prox1a / prospero homeobox 1a / PROX1* / Q92786* / P48437* / prospero homeobox 1* / Prospero homeobox protein 1 *ENSDARG0000005515823
prox2 / prospero homeobox 2 / Q3B8N5* / Q8BII1* / Prospero homeobox protein 2 *ENSDARG0000004195222


Protein motifs (from Interpro)
Interpro ID Name
 IPR009057  Homeobox-like domain superfamily
 IPR023082  Homeo-prospero domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0001946 lymphangiogenesis IMP
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0055007 cardiac muscle cell differentiation IBA
 biological_processGO:0060836 lymphatic endothelial cell differentiation IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0005110 thoracic duct thoracic duct aplastic , abnormal
thoracic duct decreased length , abnormal
Show

 ZFA:0005258 lymph vessel endothelium lymph vessel endothelium aplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr