ENSDARG00000089724


Danio rerio

Features
Gene ID: ENSDARG00000089724
  
Biological name :cyldb
  
Synonyms : cyldb / cylindromatosis (turban tumor syndrome), b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 25276748
Gene end: 25291709
  
Corresponding Affymetrix probe sets: Dr.23304.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107136
Ensembl peptide - ENSDARP00000153429
NCBI entrez gene - 564158     See in Manteia.
RefSeq - XM_009306058
swissprot - E7F048
ZFIN ID - ZDB-GENE-100208-1
Ensembl - ENSDARG00000089724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cylda / cylindromatosis (turban tumor syndrome), a / CYLD* / Q80TQ2* / Q9NQC7* / CYLD lysine 63 deubiquitinase* / Ubiquitin carboxyl-terminal hydrolase CYLD *ENSDARG0000006005840
cyldl / cylindromatosis (turban tumor syndrome), likeENSDARG0000009015333
si:cabz01101003.1ENSDARG0000010555114


Protein motifs (from Interpro)
Interpro ID Name
 IPR000938  CAP Gly-rich domain
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IBA
 biological_processGO:0070266 necroptotic process IBA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 biological_processGO:1904888 cranial skeletal system development IMP
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IBA
 biological_processGO:2001242 regulation of intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IBA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0061578 Lys63-specific deubiquitinase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk necrotic , abnormal
trunk bent , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage morphology , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage shape , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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