ENSDARG00000091777


Danio rerio

Features
Gene ID: ENSDARG00000091777
  
Biological name :mapkap1
  
Synonyms : mapkap1 / mitogen-activated protein kinase associated protein 1
  
Possible biological names infered from orthology : Q8BKH7 / Q9BPZ7 / Target of rapamycin complex 2 subunit MAPKAP1
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 5398966
Gene end: 5499956
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000111582
Ensembl peptide - ENSDARP00000117150
NCBI entrez gene - 100537196     See in Manteia.
swissprot - E7EZP2
swissprot - E9QIJ2
ZFIN ID - ZDB-GENE-041111-178
Ensembl - ENSDARG00000091777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9W6S3ENSGALG00000000977Gallus gallus
 Q9BPZ7ENSG00000119487Homo sapiens
 Q8BKH7ENSMUSG00000038696Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031313  SAPK-interacting protein 1, Pleckstrin-homology domain
 IPR031567  Sin1, middle CRIM domain
 IPR032679  Sin1, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030950 establishment or maintenance of actin cytoskeleton polarity IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0038203 TORC2 signaling IBA
 biological_processGO:0060491 regulation of cell projection assembly IMP
 biological_processGO:0090134 cell migration involved in mesendoderm migration IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0031932 TORC2 complex IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IBA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000060 prechordal plate prechordal plate decreased speed , abnormal
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 ZFA:0001204 axial mesoderm axial mesoderm increased width , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr