ENSDARG00000098334


Danio rerio

Features
Gene ID: ENSDARG00000098334
  
Biological name :exosc3
  
Synonyms : exosc3 / exosome component 3
  
Possible biological names infered from orthology : Exosome complex component RRP40 / Q7TQK4 / Q9NQT5
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 52476520
Gene end: 52480661
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000137440
NCBI entrez gene - 565000     See in Manteia.
RefSeq - NM_001029961
RefSeq Peptide - NP_001025132
swissprot - A0A0R4IRK6
ZFIN ID - ZDB-GENE-050706-140
Ensembl - ENSDARG00000098334
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXOSC3ENSGALG00000002426Gallus gallus
 EXOSC3ENSG00000107371Homo sapiens
 Exosc3ENSMUSG00000028322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004088  K Homology domain, type 1
 IPR012340  Nucleic acid-binding, OB-fold
 IPR026699  Exosome complex RNA-binding protein 1/RRP40/RRP4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0021693 cerebellar Purkinje cell layer structural organization IMP
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
hindbrain morphology , abnormal
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 ZFA:0000075 spinal cord spinal cord curved , abnormal
spinal cord decreased thickness , abnormal
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 ZFA:0000100 cerebellum cerebellum structure , abnormal
cerebellum Purkinje cell distributed , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye malformed , abnormal
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 ZFA:0000664 cranial nerve VII cranial nerve VII morphology , abnormal
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 ZFA:0001094 whole organism whole organism movement quality , abnormal
whole organism dead , abnormal
whole organism increased amount , abnormal
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 ZFA:0009052 motor neuron motor neuron axon truncated , abnormal
motor neuron axon branchiness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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