ENSGALG00000002426


Gallus gallus

Features
Gene ID: ENSGALG00000002426
  
Biological name :EXOSC3
  
Synonyms : EXOSC3 / exosome component 3
  
Possible biological names infered from orthology : Exosome complex component RRP40 / Q7TQK4 / Q9NQT5
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 4414242
Gene end: 4417915
  
Corresponding Affymetrix probe sets: Gga.5308.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003808
NCBI entrez gene - 423626     See in Manteia.
RefSeq - NM_001199516
RefSeq - XM_015288004
RefSeq Peptide - NP_001186445
swissprot - F1NWK4
Ensembl - ENSGALG00000002426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exosc3ENSDARG00000098334Danio rerio
 EXOSC3ENSG00000107371Homo sapiens
 Exosc3ENSMUSG00000028322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004088  K Homology domain, type 1
 IPR012340  Nucleic acid-binding, OB-fold
 IPR026699  Exosome complex RNA-binding protein 1/RRP40/RRP4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000467 exonucleolytic trimming to generate mature 3"-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IBA
 biological_processGO:0034475 U4 snRNA 3"-end processing IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay IEA
 biological_processGO:0045006 DNA deamination IEA
 biological_processGO:0045190 isotype switching IEA
 biological_processGO:0045830 positive regulation of isotype switching IEA
 biological_processGO:0071034 CUT catabolic process IEA
 biological_processGO:0071035 nuclear polyadenylation-dependent rRNA catabolic process IBA
 biological_processGO:0071038 nuclear polyadenylation-dependent tRNA catabolic process IBA
 biological_processGO:0071049 nuclear retention of pre-mRNA with aberrant 3"-ends at the site of transcription IBA
 biological_processGO:0071051 polyadenylation-dependent snoRNA 3"-end processing IBA
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IEA
 cellular_componentGO:0000177 cytoplasmic exosome (RNase complex) IEA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0035327 transcriptionally active chromatin IEA
 molecular_functionGO:0003723 RNA binding IBA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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