ENSDARG00000098414


Danio rerio

Features
Gene ID: ENSDARG00000098414
  
Biological name :ninl
  
Synonyms : ninein-like / ninl
  
Possible biological names infered from orthology : Ninein-like protein / Q6ZQ12 / Q9Y2I6
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 7171066
Gene end: 7233811
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000141752
NCBI entrez gene - 561921     See in Manteia.
RefSeq - NM_001281798
RefSeq Peptide - NP_001268727
swissprot - A0A0G2LAC3
ZFIN ID - ZDB-GENE-130530-768
Ensembl - ENSDARG00000098414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000023506Gallus gallus
 NINLENSG00000101004Homo sapiens
 NinlENSMUSG00000068115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nin / ninein (GSK3B interacting protein) / ninein* / Q61043* / Q8N4C6*ENSDARG0000006029821


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034454 microtubule anchoring at centrosome IBA
 biological_processGO:0035845 photoreceptor cell outer segment organization IMP
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0051642 centrosome localization IBA
 biological_processGO:0090222 centrosome-templated microtubule nucleation IBA
 cellular_componentGO:0000242 pericentriolar material IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005814 centriole IBA
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0036449 microtubule minus-end IBA
 cellular_componentGO:0097431 mitotic spindle pole IBA
 cellular_componentGO:0097539 ciliary transition fiber IBA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
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 ZFA:0000151 pronephros pronephros cystic , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis curved ventral , abnormal
whole organism anterior-posterior axis increased curvature , abnormal
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 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
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 ZFA:0001261 ventricular system ventricular system dilated , abnormal
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 ZFA:0001557 pronephric glomerulus pronephric glomerulus dilated , abnormal
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 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell lacks parts or has fewer parts of type eye photoreceptor cell photoreceptor inner segment, abnormal
eye photoreceptor cell photoreceptor outer segment decreased length , abnormal
eye photoreceptor cell vacuolated , abnormal
eye photoreceptor cell decreased distribution , abnormal
eye photoreceptor cell lacks parts or has fewer parts of type eye photoreceptor cell photoreceptor outer segment, abnormal
eye photoreceptor cell photoreceptor outer segment morphology , abnormal
eye photoreceptor cell photoreceptor outer segment has extra parts of type eye photoreceptor cell vesicle, abnormal
eye photoreceptor cell photoreceptor inner segment malformed , abnormal
eye photoreceptor cell photoreceptor inner segment has extra parts of type eye photoreceptor cell lysosome, abnormal
eye photoreceptor cell photoreceptor inner segment accumulation eye photoreceptor cell vacuole, abnormal
eye photoreceptor cell photoreceptor inner segment accumulation eye photoreceptor cell vesicle, abnormal
eye photoreceptor cell Golgi apparatus swollen , abnormal
eye photoreceptor cell Golgi stack distended , abnormal
eye photoreceptor cell cell body mislocalised , abnormal
eye photoreceptor cell photoreceptor disc membrane deformed , abnormal
eye photoreceptor cell photoreceptor inner segment has extra parts of type eye photoreceptor cell vesicle, abnormal
eye photoreceptor cell accumulation eye photoreceptor cell vacuole, abnormal
eye photoreceptor cell accumulation eye photoreceptor cell vesicle, abnormal
eye photoreceptor cell photoreceptor outer segment structure , abnormal
eye photoreceptor cell photoreceptor outer segment decreased amount , abnormal
eye photoreceptor cell axoneme decreased length , abnormal
eye photoreceptor cell protein localization disrupted , abnormal
eye photoreceptor cell mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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