ENSDARG00000098883


Danio rerio

Features
Gene ID: ENSDARG00000098883
  
Biological name :stac3
  
Synonyms : Q6DBR6 / SH3 and cysteine rich domain 3 / stac3
  
Possible biological names infered from orthology : Q8BZ71 / Q96MF2 / SH3 and cysteine-rich domain-containing protein 3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 307863
Gene end: 321351
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147661
Ensembl peptide - ENSDARP00000151899
Ensembl peptide - ENSDARP00000131553
Ensembl peptide - ENSDARP00000133228
NCBI entrez gene - 445111     See in Manteia.
swissprot - A0A0R4IBQ8
swissprot - Q6DBR6
ZFIN ID - ZDB-GENE-040801-248
Ensembl - ENSDARG00000098883
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAC3ENSG00000185482Homo sapiens
 Stac3ENSMUSG00000040287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stac / SH3 and cysteine rich domain / P97306* / Q99469* / src homology three (SH3) and cysteine rich domain*ENSDARG0000007400431


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IMP
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
 biological_processGO:0033292 T-tubule organization IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:1901387 positive regulation of voltage-gated calcium channel activity ISS
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005891 voltage-gated calcium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane ISS
 cellular_componentGO:0042383 sarcolemma IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005277 skeletal muscle skeletal muscle sarcoplasmic reticulum swollen , abnormal
Show

 ZFA:0009114 muscle cell muscle cell broken , abnormal
muscle cell L-type voltage-gated calcium channel complex decreased amount , abnormal
muscle cell release of sequestered calcium ion into cytosol by sarcoplasmic reticulum decreased process quality , abnormal
muscle cell L-type voltage-gated calcium channel complex structure , abnormal
muscle cell L-type voltage-gated calcium channel complex amount , ameliorated
muscle cell release of sequestered calcium ion into cytosol by sarcoplasmic reticulum process quality , ameliorated
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell T-tubule decreased amount , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell morphology , abnormal
slow muscle cell decreased amount , abnormal
slow muscle cell muscle contraction process quality , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell muscle contraction process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr