ENSDARG00000101180


Danio rerio

Features
Gene ID: ENSDARG00000101180
  
Biological name :mcm7
  
Synonyms : mcm7 / minichromosome maintenance complex component 7
  
Possible biological names infered from orthology : P33993 / Q61881
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 94603
Gene end: 102022
  
Corresponding Affymetrix probe sets: Dr.1055.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130215
Ensembl peptide - ENSDARP00000132487
Ensembl peptide - ENSDARP00000135317
Ensembl peptide - ENSDARP00000138542
Ensembl peptide - ENSDARP00000140539
swissprot - A0A0E3D6N5
swissprot - A0A0J9YJK4
swissprot - A0A0R4IF39
swissprot - A0A0R4IM40
swissprot - A0A0R4IRW9
ZFIN ID - ZDB-GENE-020419-27
Ensembl - ENSDARG00000101180
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCM7ENSG00000166508Homo sapiens
 Mcm7ENSMUSG00000029730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcm9 / minichromosome maintenance 9 homologous recombination repair factor / Q2KHI9* / Q9NXL9*ENSDARG0000001352827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001208  MCM domain
 IPR008050  DNA replication licensing factor Mcm7
 IPR012340  Nucleic acid-binding, OB-fold
 IPR018525  Mini-chromosome maintenance, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031327  Mini-chromosome maintenance protein
 IPR033762  MCM OB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0042555 MCM complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye necrotic , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism bent , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head necrotic , abnormal
head edematous , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk bent , abnormal
trunk necrotic , abnormal
trunk curved dorsal , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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