ENSDARG00000102128


Danio rerio

Features
Gene ID: ENSDARG00000102128
  
Biological name :eps8
  
Synonyms : epidermal growth factor receptor pathway substrate 8 / eps8
  
Possible biological names infered from orthology : Epidermal growth factor receptor kinase substrate 8 / Q08509 / Q12929
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 151506
Gene end: 178510
  
Corresponding Affymetrix probe sets: Dr.12062.1.S1_at (Zebrafish Array)   NM_200242_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000134730
Ensembl peptide - ENSDARP00000133193
NCBI entrez gene - 393212     See in Manteia.
RefSeq - NM_200242
RefSeq - XM_005168496
RefSeq - XM_009299921
RefSeq Peptide - NP_956536
swissprot - F1QMN2
swissprot - A0A0R4IID9
ZFIN ID - ZDB-GENE-040426-871
Ensembl - ENSDARG00000102128
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000013091Gallus gallus
 EPS8ENSG00000151491Homo sapiens
 Eps8ENSMUSG00000015766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eps8l2 / EPS8 like 2 / Q99K30* / Q9H6S3* / Epidermal growth factor receptor kinase substrate 8-like protein 2 *ENSDARG0000005810838
eps8l3b / EPS8-like 3b / Q91WL0* / EPS8L3* / Q8TE67* / EPS8 like 3* / Epidermal growth factor receptor kinase substrate 8-like protein 3 *ENSDARG0000000570424
eps8l3a / EPS8-like 3a / Q91WL0* / EPS8L3* / Q8TE67* / EPS8 like 3* / Epidermal growth factor receptor kinase substrate 8-like protein 3 *ENSDARG0000010197923
eps8l1 / eps8-like1 / Q8R5F8* / Q8TE68* / Epidermal growth factor receptor kinase substrate 8-like protein 1 *ENSDARG0000005798421
si:ch73-70c5.1 / Q8TE68* / EPS8L1* / Q8R5F8* / EPS8 like 1* / Epidermal growth factor receptor kinase substrate 8-like protein 1 *ENSDARG0000000331321
si:dkey-287h13.1 / Q9H6S3* / EPS8L2* / Q99K30* / EPS8 like 2* / Epidermal growth factor receptor kinase substrate 8-like protein 2 *ENSDARG0000006901112


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR030222  Epidermal growth factor receptor kinase substrate 8
 IPR033928  Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain
 IPR035462  Eps8, SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0035591 signaling adaptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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