ENSDARG00000102889


Danio rerio

Features
Gene ID: ENSDARG00000102889
  
Biological name :sept15
  
Synonyms : sept15 / septin 15
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 12853111
Gene end: 12906901
  
Corresponding Affymetrix probe sets: Dr.13341.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134927
Ensembl peptide - ENSDARP00000136282
Ensembl peptide - ENSDARP00000135914
NCBI entrez gene - 792259     See in Manteia.
RefSeq - XM_005163083
RefSeq - XM_005163084
RefSeq - NM_001077743
RefSeq Peptide - NP_001071211
swissprot - A0JMF4
swissprot - A0A0R4IPW8
swissprot - A0A0R4IN26
ZFIN ID - ZDB-GENE-061103-265
Ensembl - ENSDARG00000102889
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sept7a / septin 7a / SEPT7* / Q16181* / septin 7* / septin-7 isoform 2 *ENSDARG0000008764787
sept7b / septin 7b / SEPT7* / Q16181* / septin 7* / septin-7 isoform 2 *ENSDARG0000005267376
sept2 / septin 2 / P42208* / Q15019*ENSDARG0000002759046
sept5a / septin 5a / SEPT5* / Q9Z2Q6* / Q99719* / septin 5* / AC000093.1*ENSDARG0000001384345
SEPT4 / septin-4 / O43236*ENSDARG0000010527145
sept5b / septin 5bENSDARG0000003603144
sept4a / septin 4a / SEPT4* / O43236* / septin 4*ENSDARG0000001038544
sept12 / septin 12 / Q8IYM1*ENSDARG0000001919134
sept3 / A2BGU8 / septin 3 / Q9UH03* / Q9Z1S5* / Neuronal-specific septin-3 *ENSDARG0000003065634
sept9b / septin 9b / SEPT9* / Q9UHD8* / Q80UG5* / septin 9*ENSDARG0000010390033
sept9a / septin 9a / SEPT9* / Q9UHD8* / Q80UG5* / septin 9*ENSDARG0000002023533
zgc:63587ENSDARG0000001714033
zgc:162239 / SEPT4* / O43236* / P28661* / septin 4*ENSDARG0000001965125


Protein motifs (from Interpro)
Interpro ID Name
 IPR008115  Septin 7
 IPR016491  Septin
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030379  Septin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0042742 defense response to bacterium IMP
 biological_processGO:0055003 cardiac myofibril assembly IMP
 biological_processGO:0060048 cardiac muscle contraction IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0072114 pronephros morphogenesis IMP
 cellular_componentGO:0031105 septin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle motile cilium decreased length , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle absent , abnormal
cardiac ventricle decreased size , abnormal
Show

 ZFA:0000017 endoderm endoderm absent , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
heart morphology , abnormal
heart absent , abnormal
heart striated muscle myosin thick filament disorganized , abnormal
heart striated muscle thin filament disorganized , abnormal
heart striated muscle thin filament decreased amount , abnormal
heart Z disc structure , abnormal
heart Z disc absent , abnormal
heart Z disc disorganized , abnormal
heart cardiac myofibril disorganized , abnormal
heart decreased amount , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm bilateral symmetry , abnormal
Show

 ZFA:0000140 pancreas pancreas pancreatic A cell differentiation decreased occurrence , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0000360 heart tube heart tube bilateral symmetry , abnormal
Show

 ZFA:0000471 atrium atrium elongated , abnormal
Show

 ZFA:0000938 central canal central canal has fewer parts of type ependymal cell cilium, abnormal
Show

 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism decreased amount , abnormal
whole organism glucose increased amount , abnormal
whole organism glucose homeostasis decreased process quality , abnormal
whole organism anterior region decreased amount , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased length , abnormal
exocrine pancreas malformed , abnormal
exocrine pancreas mislocalised , abnormal
Show

 ZFA:0001260 endocrine pancreas endocrine pancreas has fewer parts of type pancreatic B cell , abnormal
endocrine pancreas has fewer parts of type pancreatic A cell , abnormal
Show

 ZFA:0001558 pronephric tubule pronephric tubule increased diameter , abnormal
pronephric tubule motile cilium disoriented , abnormal
pronephric tubule ciliary basal body disorganized , abnormal
pronephric tubule dilated , abnormal
pronephric tubule has fewer parts of type pronephric tubule microvillus, abnormal
pronephric tubule actin cytoskeleton decreased object quality , abnormal
pronephric tubule apical part of cell physical object quality , abnormal
pronephric tubule motile cilium decreased length , abnormal
Show

 ZFA:0001673 pronephric podocyte pronephric podocyte lacks parts or has fewer parts of type pronephric podocyte slit diaphragm, abnormal
pronephric podocyte cell projection malformed , abnormal
pronephric podocyte apical part of cell malformed , abnormal
Show

 ZFA:0005123 gut epithelium gut epithelium mislocalised , abnormal
Show

 ZFA:0005145 muscle muscle muscle tendon junction absent , abnormal
Show

 ZFA:0005312 pronephric capsular space pronephric capsular space dilated , abnormal
Show

 ZFA:0005748 intrapancreatic duct intrapancreatic duct mislocalised , abnormal
Show

 ZFA:0005755 islet islet cell differentiation decreased process quality , abnormal
Show

 ZFA:0009033 ependymal cell ependymal cell cilium decreased length , abnormal
ependymal cell cilium disoriented , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell cell proliferation decreased occurrence , abnormal
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
neutrophil decreased amount , exacerbated
neutrophil decreased amount , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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