ENSDARG00000103007


Danio rerio

Features
Gene ID: ENSDARG00000103007
  
Biological name :rps3
  
Synonyms : ribosomal protein S3 / rps3
  
Possible biological names infered from orthology : P23396 / P62908
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 3037998
Gene end: 3052284
  
Corresponding Affymetrix probe sets: Dr.5705.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000132180
Ensembl peptide - ENSDARP00000153775
swissprot - Q6TLG8
ZFIN ID - ZDB-GENE-030131-8494
Ensembl - ENSDARG00000103007
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPS3ENSGALG00000017330Gallus gallus
 RPS3ENSG00000149273Homo sapiens
 Rps3ENSMUSG00000030744Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001351  Ribosomal protein S3, C-terminal
 IPR004044  K Homology domain, type 2
 IPR005703  Ribosomal protein S3, eukaryotic/archaeal
 IPR009019  K homology domain superfamily, prokaryotic type
 IPR015946  K homology domain-like, alpha/beta
 IPR018280  Ribosomal protein S3, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0015935 small ribosomal subunit IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball opaque , abnormal
ball deformed , abnormal
Show

 ZFA:0000008 brain brain aplastic , abnormal
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 ZFA:0000035 lens lens decreased size , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary aplastic , abnormal
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 ZFA:0000079 telencephalon telencephalon hypoplastic , abnormal
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 ZFA:0000100 cerebellum cerebellum aplastic , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
extension deformed , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000108 fin fin decreased thickness , abnormal
fin aplastic , abnormal
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 ZFA:0000109 forebrain forebrain protruding , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle decreased size , abnormal
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 ZFA:0000128 midbrain midbrain aplastic , abnormal
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 ZFA:0000138 otic placode otic placode decreased size , abnormal
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 ZFA:0000152 retina retina decreased size , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001117 post-vent region post-vent region bent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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