ENSMUSG00000030744


Mus musculus

Features
Gene ID: ENSMUSG00000030744
  
Biological name :Rps3
  
Synonyms : P62908 / ribosomal protein S3 / Rps3
  
Possible biological names infered from orthology : P23396
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E1
Gene start: 99477896
Gene end: 99483738
  
Corresponding Affymetrix probe sets: 10565802 (MoGene1.0st)   10565811 (MoGene1.0st)   1435151_a_at (Mouse Genome 430 2.0 Array)   1447563_at (Mouse Genome 430 2.0 Array)   1455600_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032998
Ensembl peptide - ENSMUSP00000146709
Ensembl peptide - ENSMUSP00000102713
NCBI entrez gene - 27050     See in Manteia.
MGI - MGI:1350917
RefSeq - NM_012052
RefSeq Peptide - NP_036182
swissprot - A0A140LI77
swissprot - D3YV43
swissprot - P62908
swissprot - Q5YLW3
Ensembl - ENSMUSG00000030744
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps3ENSDARG00000103007Danio rerio
 RPS3ENSGALG00000017330Gallus gallus
 RPS3ENSG00000149273Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001351  Ribosomal protein S3, C-terminal
 IPR004044  K Homology domain, type 2
 IPR005703  Ribosomal protein S3, eukaryotic/archaeal
 IPR009019  K homology domain superfamily, prokaryotic type
 IPR015946  K homology domain-like, alpha/beta
 IPR018280  Ribosomal protein S3, conserved site
 IPR036419  Ribosomal protein S3, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0031334 positive regulation of protein complex assembly IMP
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0032079 positive regulation of endodeoxyribonuclease activity IEA
 biological_processGO:0032743 positive regulation of interleukin-2 production IEA
 biological_processGO:0042104 positive regulation of activated T cell proliferation IEA
 biological_processGO:0042769 DNA damage response, detection of DNA damage IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0045738 negative regulation of DNA repair IEA
 biological_processGO:0045739 positive regulation of DNA repair IEA
 biological_processGO:0050862 positive regulation of T cell receptor signaling pathway IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0051225 spindle assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0061481 response to TNF agonist IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:1902546 positive regulation of DNA N-glycosylase activity IEA
 biological_processGO:1905053 positive regulation of base-excision repair IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 biological_processGO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005844 polysome IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015935 small ribosomal subunit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031012 extracellular matrix ISO
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0071159 NF-kappaB complex IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity ISO
 molecular_functionGO:0004520 endodeoxyribonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity IBA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0032357 oxidized purine DNA binding IEA
 molecular_functionGO:0032358 oxidized pyrimidine DNA binding IEA
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051018 protein kinase A binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding IEA
 molecular_functionGO:0070181 small ribosomal subunit rRNA binding IEA
 molecular_functionGO:0097100 supercoiled DNA binding IEA
 molecular_functionGO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:0140080 class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity IEA


Pathways (from Reactome)
Pathway description
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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