ENSDARG00000104138


Danio rerio

Features
Gene ID: ENSDARG00000104138
  
Biological name :igfbp7
  
Synonyms : igfbp7 / insulin-like growth factor binding protein 7
  
Possible biological names infered from orthology : Q16270
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 52369262
Gene end: 52379718
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000139497
Ensembl peptide - ENSDARP00000141482
swissprot - A0A0R4IU08
swissprot - A0A0R4IZL1
ZFIN ID - ZDB-GENE-040426-2423
Ensembl - ENSDARG00000104138
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037332Gallus gallus
 IGFBP7ENSG00000163453Homo sapiens
 Igfbp7ENSMUSG00000036256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kazald2 / Kazal-type serine peptidase inhibitor domain 2ENSDARG0000007851831
kazald3 / Kazal-type serine peptidase inhibitor domain 3 / Q8BJ66* / Q96I82* / KAZALD1* / Kazal type serine peptidase inhibitor domain 1* / Kazal-type serine protease inhibitor domain-conta...ENSDARG0000005350928


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR002350  Kazal domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011390  Insulin-like growth factor binding protein-related protein (IGFBP-rP), MAC25
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0002040 sprouting angiogenesis IGI
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000106 extension extension morphology , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel irregular spatial pattern , abnormal
intersegmental vessel decreased length , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel hypoplastic , abnormal
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 ZFA:0009044 blood cell blood cell decreased amount , abnormal
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 ZFA:0009091 melanocyte melanocyte absent , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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