ENSDARG00000104541


Danio rerio

Features
Gene ID: ENSDARG00000104541
  
Biological name :msh6
  
Synonyms : msh6 / mutS homolog 6 (E. coli)
  
Possible biological names infered from orthology : DNA mismatch repair protein Msh6 / mutS homolog 6 / P52701 / P54276
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 48358467
Gene end: 48381055
  
Corresponding Affymetrix probe sets: Dr.4108.1.S1_at (Zebrafish Array)   NM_182860_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130154
Ensembl peptide - ENSDARP00000140704
Ensembl peptide - ENSDARP00000133896
Ensembl peptide - ENSDARP00000131172
NCBI entrez gene - 260437     See in Manteia.
RefSeq - NM_182860
RefSeq Peptide - NP_878280
swissprot - A0A0R4IAE0
swissprot - A0A0R4IYP8
swissprot - A0A0R4I9L0
swissprot - A0A0R4IFF9
ZFIN ID - ZDB-GENE-020905-3
Ensembl - ENSDARG00000104541
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MSH6ENSGALG00000008957Gallus gallus
 MSH6ENSG00000116062Homo sapiens
 Msh6ENSMUSG00000005370Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR000432  DNA mismatch repair protein MutS, C-terminal
 IPR007695  DNA mismatch repair protein MutS-like, N-terminal
 IPR007696  DNA mismatch repair protein MutS, core
 IPR007860  DNA mismatch repair protein MutS, connector domain
 IPR007861  DNA mismatch repair protein MutS, clamp
 IPR015536  DNA mismatch repair protein MutS-homologue MSH6
 IPR016151  DNA mismatch repair protein MutS, N-terminal
 IPR017261  DNA mismatch repair protein MutS/MSH
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006298 mismatch repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0043570 maintenance of DNA repeat elements IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030983 mismatched DNA binding IEA
 molecular_functionGO:0032137 guanine/thymine mispair binding IGI


Pathways (from Reactome)
Pathway description
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism neoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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