ENSG00000001036


Homo sapiens

Features
Gene ID: ENSG00000001036
  
Biological name :FUCA2
  
Synonyms : alpha-L-fucosidase 2 / FUCA2 / Q9BTY2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q24.2
Gene start: 143494811
Gene end: 143511690
  
Corresponding Affymetrix probe sets: 223120_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000002165
Ensembl peptide - ENSP00000398119
NCBI entrez gene - 2519     See in Manteia.
OMIM - 136820
RefSeq - NM_032020
RefSeq Peptide - NP_114409
swissprot - Q7Z6V2
swissprot - Q9BTY2
Ensembl - ENSG00000001036
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fuca2ENSDARG00000044073Danio rerio
 FUCA2ENSGALG00000013773Gallus gallus
 Fuca2ENSMUSG00000019810Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FUCA1 / P04066 / alpha-L-fucosidase 1ENSG0000017916354


Protein motifs (from Interpro)
Interpro ID Name
 IPR000933  Glycoside hydrolase, family 29
 IPR016286  Alpha-L-fucosidase, metazoa-type
 IPR017853  Glycoside hydrolase superfamily
 IPR018526  Glycoside hydrolase, family 29, conserved site
 IPR031919  Alpha-L-fucosidase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006004 fucose metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0016139 glycoside catabolic process IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:2000535 regulation of entry of bacterium into host cell IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004560 alpha-L-fucosidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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