ENSG00000004468


Homo sapiens

Features
Gene ID: ENSG00000004468
  
Biological name :CD38
  
Synonyms : CD38 / CD38 molecule / P28907
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p15.32
Gene start: 15778275
Gene end: 15853230
  
Corresponding Affymetrix probe sets: 205692_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427277
Ensembl peptide - ENSP00000226279
Ensembl peptide - ENSP00000423047
NCBI entrez gene - 952     See in Manteia.
OMIM - 107270
RefSeq - NM_001775
RefSeq Peptide - NP_001766
swissprot - H0Y950
swissprot - P28907
Ensembl - ENSG00000004468
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR318624.2ENSDARG00000113438Danio rerio
 CD38ENSGALG00000014508Gallus gallus
 Cd38ENSMUSG00000029084Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BST1 / Q10588 / bone marrow stromal cell antigen 1ENSG0000010974331


Protein motifs (from Interpro)
Interpro ID Name
 IPR003193  ADP-ribosyl cyclase (CD38/157)
 IPR033567  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0019674 NAD metabolic process TAS
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0033194 response to hydroperoxide IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045779 negative regulation of bone resorption IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0050853 B cell receptor signaling pathway IMP
 biological_processGO:0060292 long term synaptic depression IEA
 biological_processGO:0070555 response to interleukin-1 IEA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003953 NAD+ nucleosidase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0050135 NAD(P)+ nucleosidase activity IEA
 molecular_functionGO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating IEA


Pathways (from Reactome)
Pathway description
Nicotinate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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