ENSG00000109743


Homo sapiens

Features
Gene ID: ENSG00000109743
  
Biological name :BST1
  
Synonyms : bone marrow stromal cell antigen 1 / BST1 / Q10588
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p15.32
Gene start: 15702950
Gene end: 15738313
  
Corresponding Affymetrix probe sets: 205715_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265016
Ensembl peptide - ENSP00000420925
Ensembl peptide - ENSP00000423357
Ensembl peptide - ENSP00000424761
Ensembl peptide - ENSP00000371783
NCBI entrez gene - 683     See in Manteia.
OMIM - 600387
RefSeq - XM_017008567
RefSeq - XM_005248186
RefSeq - XM_011513878
RefSeq - XM_011513879
RefSeq - XM_011513881
RefSeq - XM_017008565
RefSeq - XM_017008566
RefSeq - NM_004334
RefSeq - XM_005248185
RefSeq Peptide - NP_004325
swissprot - H0Y8G4
swissprot - H0Y984
swissprot - H0Y9Q9
swissprot - A6NC48
swissprot - Q10588
Ensembl - ENSG00000109743
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR318624.2ENSDARG00000113438Danio rerio
 BST1ENSGALG00000014509Gallus gallus
 Bst1ENSMUSG00000029082Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD38 / P28907 / CD38 moleculeENSG0000000446829


Protein motifs (from Interpro)
Interpro ID Name
 IPR003193  ADP-ribosyl cyclase (CD38/157)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001952 regulation of cell-matrix adhesion IDA
 biological_processGO:0002691 regulation of cellular extravasation TAS
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006959 humoral immune response IC
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0019674 NAD metabolic process TAS
 biological_processGO:0030890 positive regulation of B cell proliferation IBA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050727 regulation of inflammatory response IDA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0050848 regulation of calcium-mediated signaling TAS
 biological_processGO:0090022 regulation of neutrophil chemotaxis IDA
 biological_processGO:0090322 regulation of superoxide metabolic process TAS
 biological_processGO:2001044 regulation of integrin-mediated signaling pathway TAS
 cellular_componentGO:0001931 uropod IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008305 integrin complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003953 NAD+ nucleosidase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IBA
 molecular_functionGO:0050135 NAD(P)+ nucleosidase activity IEA
 molecular_functionGO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating IEA
 molecular_functionGO:0061811 ADP-ribosyl cyclase activity IDA
 molecular_functionGO:0061812 cyclic ADP-ribose hydrolase IDA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Nicotinate metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109743 BST1 / Q10588 / bone marrow stromal cell antigen 1  / complex






 

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