ENSMUSG00000029082


Mus musculus

Features
Gene ID: ENSMUSG00000029082
  
Biological name :Bst1
  
Synonyms : bone marrow stromal cell antigen 1 / Bst1
  
Possible biological names infered from orthology : Q10588
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B3
Gene start: 43818885
Gene end: 43843986
  
Corresponding Affymetrix probe sets: 10521667 (MoGene1.0st)   1449453_at (Mouse Genome 430 2.0 Array)   1449454_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098796
Ensembl peptide - ENSMUSP00000143382
NCBI entrez gene - 12182     See in Manteia.
MGI - MGI:105370
RefSeq - NM_009763
RefSeq - XM_006503706
RefSeq Peptide - NP_033893
swissprot - A0A0R4J190
swissprot - A0A0G2JG11
Ensembl - ENSMUSG00000029082
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR318624.2ENSDARG00000113438Danio rerio
 BST1ENSGALG00000014509Gallus gallus
 BST1ENSG00000109743Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd38 / P56528 / ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 / P28907* / CD38 molecule*ENSMUSG0000002908430


Protein motifs (from Interpro)
Interpro ID Name
 IPR003193  ADP-ribosyl cyclase (CD38/157)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001952 regulation of cell-matrix adhesion IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050848 regulation of calcium-mediated signaling IEA
 biological_processGO:0090022 regulation of neutrophil chemotaxis IEA
 cellular_componentGO:0001931 uropod IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0019898 extrinsic component of membrane IEA
 molecular_functionGO:0003953 NAD+ nucleosidase activity IEA
 molecular_functionGO:0061811 ADP-ribosyl cyclase activity IEA
 molecular_functionGO:0061812 cyclic ADP-ribose hydrolase IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Nicotinate metabolism
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001800 abnormal humoral immune response "abnormal immune function mediated by antibodies" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0001807 decreased IgA "less than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0004978 decreased B-1 B cell number "reduced number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0008215 decreased immature B cell number "reduced number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

 MP:0008498 decreased IgG3 level "less than normal immunoglobulin class G3 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Tyrp1B-lt/Tyrp1+
Genetic Background: C58

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029082 Bst1 / bone marrow stromal cell antigen 1 / Q10588*  / complex






 

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