ENSG00000004776


Homo sapiens

Features
Gene ID: ENSG00000004776
  
Biological name :HSPB6
  
Synonyms : heat shock protein family B (small) member 6 / HSPB6 / O14558
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.12
Gene start: 35754569
Gene end: 35758079
  
Corresponding Affymetrix probe sets: 214767_s_at (Human Genome U133 Plus 2.0 Array)   226304_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000004982
Ensembl peptide - ENSP00000468057
Ensembl peptide - ENSP00000467169
NCBI entrez gene - 126393     See in Manteia.
OMIM - 610695
RefSeq - NM_144617
RefSeq Peptide - NP_653218
swissprot - K7EP04
swissprot - A0A1X7SC65
swissprot - O14558
swissprot - V9HWB6
Ensembl - ENSG00000004776
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hspb6ENSDARG00000077236Danio rerio
 Hspb6ENSMUSG00000036854Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CRYAB / P02511 / crystallin alpha BENSG0000010984649
CRYAA2 / crystallin alpha A2ENSG0000027607644
CRYAA / P02489 / crystallin alpha AENSG0000016020244
HSPB1 / P04792 / heat shock protein family B (small) member 1ENSG0000010621139
HSPB2 / Q16082 / heat shock protein family B (small) member 2ENSG0000017027636
HSPB2-C11orf52 / HSPB2-C11orf52 readthrough (NMD candidate)ENSG0000025444536
HSPB8 / Q9UJY1 / heat shock protein family B (small) member 8ENSG0000015213729
HSPB3 / Q12988 / heat shock protein family B (small) member 3ENSG0000016927121


Protein motifs (from Interpro)
Interpro ID Name
 IPR001436  Alpha crystallin/Heat shock protein
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR003090  Alpha-crystallin, N-terminal
 IPR008978  HSP20-like chaperone
 IPR031107  Small heat shock protein HSP20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IDA
 biological_processGO:0061077 chaperone-mediated protein folding IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005212 structural constituent of eye lens IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051082 unfolded protein binding IDA
 molecular_functionGO:0051087 chaperone binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr