ENSG00000005889


Homo sapiens

Features
Gene ID: ENSG00000005889
  
Biological name :ZFX
  
Synonyms : P17010 / ZFX / zinc finger protein, X-linked
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.11
Gene start: 24149173
Gene end: 24216255
  
Corresponding Affymetrix probe sets: 207247_s_at (Human Genome U133 Plus 2.0 Array)   207920_x_at (Human Genome U133 Plus 2.0 Array)   214678_x_at (Human Genome U133 Plus 2.0 Array)   217176_s_at (Human Genome U133 Plus 2.0 Array)   229022_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368475
Ensembl peptide - ENSP00000343384
Ensembl peptide - ENSP00000368486
Ensembl peptide - ENSP00000438233
Ensembl peptide - ENSP00000416298
Ensembl peptide - ENSP00000411637
Ensembl peptide - ENSP00000304985
NCBI entrez gene - 7543     See in Manteia.
OMIM - 314980
RefSeq - XM_017029801
RefSeq - XM_017029790
RefSeq - XM_017029791
RefSeq - XM_017029792
RefSeq - XM_017029793
RefSeq - XM_017029794
RefSeq - XM_017029795
RefSeq - XM_017029796
RefSeq - XM_017029797
RefSeq - XM_017029798
RefSeq - XM_017029799
RefSeq - XM_017029800
RefSeq - NM_001178084
RefSeq - NM_001178085
RefSeq - NM_001178086
RefSeq - NM_001178095
RefSeq - NM_001330327
RefSeq - NM_003410
RefSeq - XM_005274591
RefSeq - XM_005274592
RefSeq - XM_005274594
RefSeq - XM_006724513
RefSeq - XM_006724515
RefSeq - XM_011545578
RefSeq - XM_011545579
RefSeq - XM_011545581
RefSeq - XM_011545583
RefSeq - XM_017029788
RefSeq - XM_017029789
RefSeq Peptide - NP_001171556
RefSeq Peptide - NP_001171557
RefSeq Peptide - NP_001171566
RefSeq Peptide - NP_001317256
RefSeq Peptide - NP_003401
RefSeq Peptide - NP_001171555
swissprot - C9JGU9
swissprot - C9J682
swissprot - E9PEP7
swissprot - P17010
swissprot - A0A024RC04
Ensembl - ENSG00000005889
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079241.1ENSDARG00000098424Danio rerio
 zfxENSDARG00000074453Danio rerio
 ZfxENSMUSG00000079509Mus musculus
 Zfy1ENSMUSG00000053211Mus musculus
 Zfy2ENSMUSG00000000103Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZFY / P08048 / zinc finger protein, Y-linkedENSG0000006764680
Q9Y462 / ZNF711 / zinc finger protein 711ENSG0000014718055
Q9UID6 / ZNF639 / zinc finger protein 639ENSG0000012186410


Protein motifs (from Interpro)
Interpro ID Name
 IPR006794  Transcriptional activator, Zfx / Zfy domain
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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