ENSG00000006625


Homo sapiens

Features
Gene ID: ENSG00000006625
  
Biological name :GGCT
  
Synonyms : gamma-glutamylcyclotransferase / GGCT / O75223
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p14.3
Gene start: 30496621
Gene end: 30504844
  
Corresponding Affymetrix probe sets: 215380_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386686
Ensembl peptide - ENSP00000387235
Ensembl peptide - ENSP00000408015
Ensembl peptide - ENSP00000390094
Ensembl peptide - ENSP00000387809
Ensembl peptide - ENSP00000005374
Ensembl peptide - ENSP00000275428
Ensembl peptide - ENSP00000386610
NCBI entrez gene - 79017     See in Manteia.
OMIM - 137170
RefSeq - NM_024051
RefSeq - NM_001199815
RefSeq - NM_001199816
RefSeq - NM_001199817
RefSeq Peptide - NP_001186744
RefSeq Peptide - NP_001186745
RefSeq Peptide - NP_001186746
RefSeq Peptide - NP_076956
swissprot - O75223
swissprot - A0A0B4J1Y4
swissprot - A0A090N7V5
swissprot - H7BZK5
swissprot - B8ZZK2
Ensembl - ENSG00000006625
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ggctaENSDARG00000076406Danio rerio
 ENSGALG00000030552Gallus gallus
 GgctENSMUSG00000002797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC005154.6ENSG0000028103955


Protein motifs (from Interpro)
Interpro ID Name
 IPR013024  Gamma-glutamyl cyclotransferase-like
 IPR017939  Gamma-glutamylcyclotransferase
 IPR036568  Gamma-glutamyl cyclotransferase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001836 release of cytochrome c from mitochondria IMP
 biological_processGO:0006750 glutathione biosynthetic process TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003839 gamma-glutamylcyclotransferase activity TAS
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Glutathione synthesis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000006625 GGCT / O75223 / gamma-glutamylcyclotransferase  / complex






 

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contact: otassy@igbmc.fr