ENSG00000008838


Homo sapiens

Features
Gene ID: ENSG00000008838
  
Biological name :MED24
  
Synonyms : MED24 / mediator complex subunit 24 / O75448
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.1
Gene start: 40019097
Gene end: 40061215
  
Corresponding Affymetrix probe sets: 213043_s_at (Human Genome U133 Plus 2.0 Array)   215337_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463484
Ensembl peptide - ENSP00000463480
Ensembl peptide - ENSP00000463528
Ensembl peptide - ENSP00000482676
Ensembl peptide - ENSP00000464225
Ensembl peptide - ENSP00000463751
Ensembl peptide - ENSP00000463724
Ensembl peptide - ENSP00000348610
Ensembl peptide - ENSP00000377684
Ensembl peptide - ENSP00000377685
Ensembl peptide - ENSP00000377686
Ensembl peptide - ENSP00000392276
Ensembl peptide - ENSP00000393464
Ensembl peptide - ENSP00000435760
Ensembl peptide - ENSP00000438630
Ensembl peptide - ENSP00000438767
Ensembl peptide - ENSP00000439148
Ensembl peptide - ENSP00000440100
Ensembl peptide - ENSP00000443344
Ensembl peptide - ENSP00000462539
Ensembl peptide - ENSP00000462646
Ensembl peptide - ENSP00000463043
NCBI entrez gene - 9862     See in Manteia.
OMIM - 607000
RefSeq - XM_017025470
RefSeq - XM_006722204
RefSeq - XM_006722206
RefSeq - XM_006722207
RefSeq - XM_011525529
RefSeq - XM_011525530
RefSeq - XM_011525531
RefSeq - XM_011525532
RefSeq - XM_011525533
RefSeq - XM_011525534
RefSeq - XM_011525535
RefSeq - XM_011525536
RefSeq - XM_011525538
RefSeq - XM_017025458
RefSeq - XM_017025459
RefSeq - XM_017025460
RefSeq - XM_017025461
RefSeq - XM_017025462
RefSeq - XM_017025463
RefSeq - XM_017025464
RefSeq - XM_017025465
RefSeq - XM_017025466
RefSeq - XM_017025467
RefSeq - XM_017025468
RefSeq - XM_017025469
RefSeq - NM_001079518
RefSeq - NM_001267797
RefSeq - NM_014815
RefSeq - XM_005257874
RefSeq Peptide - NP_055630
RefSeq Peptide - NP_001072986
RefSeq Peptide - NP_001254726
RefSeq Peptide - NP_001317140
swissprot - F5GY88
swissprot - F5H0M2
swissprot - F5H2D6
swissprot - F5H3E6
swissprot - F5H5K2
swissprot - H0YEG1
swissprot - J3KSL1
swissprot - J3KSU0
swissprot - E9PFL1
swissprot - J3QLC0
swissprot - J3QLC2
swissprot - J3QLF8
swissprot - J3QLV7
swissprot - J3QRH9
swissprot - O75448
swissprot - A0A0B4J1W0
swissprot - J3KTL3
swissprot - B9TX75
swissprot - B9TX62
swissprot - B4DDR8
Ensembl - ENSG00000008838
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med24ENSDARG00000099431Danio rerio
 MED24ENSGALG00000013506Gallus gallus
 Med24ENSMUSG00000017210Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021429  Mediator complex, subunit Med24, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IDA
 biological_processGO:0030521 androgen receptor signaling pathway IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex IEA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity NAS
 molecular_functionGO:0042809 vitamin D receptor binding NAS
 molecular_functionGO:0046966 thyroid hormone receptor binding IDA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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