ENSG00000010932


Homo sapiens

Features
Gene ID: ENSG00000010932
  
Biological name :FMO1
  
Synonyms : flavin containing monooxygenase 1 / FMO1 / Q01740
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q24.3
Gene start: 171248471
Gene end: 171285978
  
Corresponding Affymetrix probe sets: 205666_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000491035
Ensembl peptide - ENSP00000356724
Ensembl peptide - ENSP00000385543
Ensembl peptide - ENSP00000481732
Ensembl peptide - ENSP00000346901
NCBI entrez gene - 2326     See in Manteia.
OMIM - 136130
RefSeq - XM_006711242
RefSeq - NM_001282692
RefSeq - NM_001282693
RefSeq - NM_001282694
RefSeq - NM_002021
RefSeq - XM_005245037
RefSeq - XM_005245038
RefSeq - XM_006711241
RefSeq Peptide - NP_002012
RefSeq Peptide - NP_001269621
RefSeq Peptide - NP_001269622
RefSeq Peptide - NP_001269623
swissprot - Q01740
swissprot - A0A1W2PNR8
swissprot - A0A024R934
Ensembl - ENSG00000010932
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmo5ENSDARG00000016357Danio rerio
 si:dkey-239i20.2ENSDARG00000043518Danio rerio
 si:dkey-239i20.4ENSDARG00000043514Danio rerio
 Fmo1ENSMUSG00000040181Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FMO2 / Q99518 / flavin containing monooxygenase 2ENSG0000009496357
FMO3 / P31513 / flavin containing monooxygenase 3ENSG0000000793355
FMO5 / P49326 / flavin containing monooxygenase 5ENSG0000013178151
FMO4 / P31512 / flavin containing monooxygenase 4ENSG0000007625851


Protein motifs (from Interpro)
Interpro ID Name
 IPR000960  Flavin monooxygenase FMO
 IPR002253  Flavin monooxygenase (FMO) 1
 IPR020946  Flavin monooxygenase-like
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006082 organic acid metabolic process IDA
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0006970 response to osmotic stress IEA
 biological_processGO:0009404 toxin metabolic process IDA
 biological_processGO:0017144 drug metabolic process IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070995 NADPH oxidation IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IDA
 molecular_functionGO:0004499 N,N-dimethylaniline monooxygenase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA


Pathways (from Reactome)
Pathway description
FMO oxidises nucleophiles


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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