ENSG00000094963


Homo sapiens

Features
Gene ID: ENSG00000094963
  
Biological name :FMO2
  
Synonyms : flavin containing monooxygenase 2 / FMO2 / Q99518
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q24.3
Gene start: 171185208
Gene end: 171211230
  
Corresponding Affymetrix probe sets: 211726_s_at (Human Genome U133 Plus 2.0 Array)   228268_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000209929
Ensembl peptide - ENSP00000487216
Ensembl peptide - ENSP00000487002
NCBI entrez gene - 2327     See in Manteia.
OMIM - 603955
RefSeq - NM_001301347
RefSeq - NM_001460
RefSeq Peptide - NP_001288276
RefSeq Peptide - NP_001451
swissprot - Q99518
swissprot - A0A0D9SFZ0
swissprot - A0A0D9SG76
Ensembl - ENSG00000094963
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmo5ENSDARG00000016357Danio rerio
 si:dkey-239i20.2ENSDARG00000043518Danio rerio
 si:dkey-239i20.4ENSDARG00000043514Danio rerio
 Fmo2ENSMUSG00000040170Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FMO1 / Q01740 / flavin containing monooxygenase 1ENSG0000001093257
FMO3 / P31513 / flavin containing monooxygenase 3ENSG0000000793356
FMO4 / P31512 / flavin containing monooxygenase 4ENSG0000007625854
FMO5 / P49326 / flavin containing monooxygenase 5ENSG0000013178154


Protein motifs (from Interpro)
Interpro ID Name
 IPR000960  Flavin monooxygenase FMO
 IPR002254  Flavin monooxygenase (FMO) 2
 IPR020946  Flavin monooxygenase-like
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006082 organic acid metabolic process IDA
 biological_processGO:0006739 NADP metabolic process IDA
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0009404 toxin metabolic process IDA
 biological_processGO:0017144 drug metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070995 NADPH oxidation IDA
 biological_processGO:0072592 oxygen metabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004499 N,N-dimethylaniline monooxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA


Pathways (from Reactome)
Pathway description
FMO oxidises nucleophiles


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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