ENSMUSG00000040170


Mus musculus

Features
Gene ID: ENSMUSG00000040170
  
Biological name :Fmo2
  
Synonyms : Dimethylaniline monooxygenase [N-oxide-forming] 2 / Fmo2 / Q8K2I3
  
Possible biological names infered from orthology : flavin containing monooxygenase 2 / Q99518
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H2.1
Gene start: 162874317
Gene end: 162898726
  
Corresponding Affymetrix probe sets: 10359582 (MoGene1.0st)   1422904_at (Mouse Genome 430 2.0 Array)   1422905_s_at (Mouse Genome 430 2.0 Array)   1435459_at (Mouse Genome 430 2.0 Array)   1453435_a_at (Mouse Genome 430 2.0 Array)   1454005_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114226
Ensembl peptide - ENSMUSP00000044405
Ensembl peptide - ENSMUSP00000107135
NCBI entrez gene - 55990     See in Manteia.
MGI - MGI:1916776
RefSeq - NM_018881
RefSeq - XM_006496949
RefSeq Peptide - NP_061369
swissprot - D3YVR1
swissprot - Q8K2I3
Ensembl - ENSMUSG00000040170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fmo5ENSDARG00000016357Danio rerio
 si:dkey-239i20.2ENSDARG00000043518Danio rerio
 si:dkey-239i20.4ENSDARG00000043514Danio rerio
 FMO2ENSG00000094963Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fmo3 / P97501 / Dimethylaniline monooxygenase [N-oxide-forming] 3 / P31513* / flavin containing monooxygenase 3*ENSMUSG0000002669156
Fmo6ENSMUSG0000009557655
Fmo9 / flavin containing monooxygenase 9 isoform 2 ENSMUSG0000002656055
Fmo1 / P50285 / Mus musculus flavin containing monooxygenase 1 (Fmo1), transcript variant 3, mRNA. / Q01740* / flavin containing monooxygenase 1*ENSMUSG0000004018155
Fmo5 / P97872 / Mus musculus flavin containing monooxygenase 5 (Fmo5), transcript variant 4, mRNA. / P49326* / flavin containing monooxygenase 5*ENSMUSG0000002808854
Fmo4 / Q8VHG0 / Dimethylaniline monooxygenase [N-oxide-forming] 4 / P31512* / flavin containing monooxygenase 4*ENSMUSG0000002669253
Gm4846ENSMUSG0000008605649
Gm4847ENSMUSG0000005108148


Protein motifs (from Interpro)
Interpro ID Name
 IPR000960  Flavin monooxygenase FMO
 IPR002254  Flavin monooxygenase (FMO) 2
 IPR020946  Flavin monooxygenase-like
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006082 organic acid metabolic process ISO
 biological_processGO:0006739 NADP metabolic process ISO
 biological_processGO:0006805 xenobiotic metabolic process ISO
 biological_processGO:0009404 toxin metabolic process ISO
 biological_processGO:0017144 drug metabolic process ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070995 NADPH oxidation ISS
 biological_processGO:0072592 oxygen metabolic process IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004499 N,N-dimethylaniline monooxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0050661 NADP binding IEA


Pathways (from Reactome)
Pathway description
FMO oxidises nucleophiles


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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