ENSG00000014123


Homo sapiens

Features
Gene ID: ENSG00000014123
  
Biological name :UFL1
  
Synonyms : O94874 / UFL1 / UFM1 specific ligase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q16.1
Gene start: 96521595
Gene end: 96555276
  
Corresponding Affymetrix probe sets: 212633_at (Human Genome U133 Plus 2.0 Array)   212634_at (Human Genome U133 Plus 2.0 Array)   238291_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358283
NCBI entrez gene - 23376     See in Manteia.
OMIM - 613372
RefSeq - NM_015323
RefSeq Peptide - NP_056138
swissprot - O94874
Ensembl - ENSG00000014123
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ufl1ENSDARG00000007496Danio rerio
 UFL1ENSGALG00000015580Gallus gallus
 Ufl1ENSMUSG00000040359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018611  E3 UFM1-protein ligase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0033146 regulation of intracellular estrogen receptor signaling pathway IDA
 biological_processGO:0034976 response to endoplasmic reticulum stress IDA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0060252 positive regulation of glial cell proliferation IEA
 biological_processGO:0071569 protein ufmylation IMP
 biological_processGO:1902065 response to L-glutamate IEA
 biological_processGO:1990592 protein K69-linked ufmylation IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0071568 UFM1 transferase activity IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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