ENSG00000014257


Homo sapiens

Features
Gene ID: ENSG00000014257
  
Biological name :ACPP
  
Synonyms : acid phosphatase, prostate / ACPP / P15309
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.1
Gene start: 132317367
Gene end: 132368298
  
Corresponding Affymetrix probe sets: 204393_s_at (Human Genome U133 Plus 2.0 Array)   231711_at (Human Genome U133 Plus 2.0 Array)   237030_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000323036
Ensembl peptide - ENSP00000417744
Ensembl peptide - ENSP00000418366
Ensembl peptide - ENSP00000422036
Ensembl peptide - ENSP00000337471
NCBI entrez gene - 55     See in Manteia.
OMIM - 171790
RefSeq - XM_011512947
RefSeq - NM_001099
RefSeq - NM_001134194
RefSeq - NM_001292037
RefSeq - XM_011512946
RefSeq Peptide - NP_001090
RefSeq Peptide - NP_001127666
RefSeq Peptide - NP_001278966
swissprot - H0Y8T3
swissprot - P15309
swissprot - E9PFE6
Ensembl - ENSG00000014257
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043415Gallus gallus
 ENSGALG00000030322Gallus gallus
 AcppENSMUSG00000032561Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACP2 / P11117 / acid phosphatase 2, lysosomalENSG0000013457546
ACP4 / Q9BZG2 / acid phosphatase 4ENSG0000014251340
ACP6 / Q9NPH0 / acid phosphatase 6, lysophosphatidicENSG0000016283623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000560  Histidine phosphatase superfamily, clade-2
 IPR029033  Histidine phosphatase superfamily
 IPR033379  Histidine acid phosphatase active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IEA
 biological_processGO:0006772 thiamine metabolic process IEA
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0016311 dephosphorylation IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046085 adenosine metabolic process IDA
 biological_processGO:0051289 protein homotetramerization IDA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 biological_processGO:0060168 positive regulation of adenosine receptor signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IMP
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003993 acid phosphatase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008253 5"-nucleotidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IMP
 molecular_functionGO:0042131 thiamine phosphate phosphatase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0052642 lysophosphatidic acid phosphatase activity IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr