ENSMUSG00000032561


Mus musculus

Features
Gene ID: ENSMUSG00000032561
  
Biological name :Acpp
  
Synonyms : Acpp / Prostatic acid phosphatase / Q8CE08
  
Possible biological names infered from orthology : acid phosphatase, prostate / P15309
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 104288251
Gene end: 104337748
  
Corresponding Affymetrix probe sets: 10596303 (MoGene1.0st)   1419832_s_at (Mouse Genome 430 2.0 Array)   1441975_at (Mouse Genome 430 2.0 Array)   1453943_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150874
Ensembl peptide - ENSMUSP00000059889
Ensembl peptide - ENSMUSP00000108209
NCBI entrez gene - 56318     See in Manteia.
MGI - MGI:1928480
RefSeq - NM_019807
RefSeq - NM_207668
RefSeq Peptide - NP_062781
RefSeq Peptide - NP_997551
swissprot - A0A1L1SUT0
swissprot - Q8CE08
Ensembl - ENSMUSG00000032561
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043415Gallus gallus
 ENSGALG00000030322Gallus gallus
 ACPPENSG00000014257Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acp2 / P24638 / Mus musculus acid phosphatase 2, lysosomal (Acp2), transcript variant 1, mRNA. / P11117* / acid phosphatase 2, lysosomal*ENSMUSG0000000210347
Acp4 / D3YTS9 / Testicular acid phosphatase / Q9BZG2* / acid phosphatase 4*ENSMUSG0000001277739
Acp6 / Q8BP40 / Lysophosphatidic acid phosphatase type 6 / Q9NPH0* / acid phosphatase 6, lysophosphatidic*ENSMUSG0000002809323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000560  Histidine phosphatase superfamily, clade-2
 IPR029033  Histidine phosphatase superfamily
 IPR033379  Histidine acid phosphatase active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006144 purine nucleobase metabolic process IMP
 biological_processGO:0006772 thiamine metabolic process IMP
 biological_processGO:0009117 nucleotide metabolic process IMP
 biological_processGO:0016311 dephosphorylation ISS
 biological_processGO:0046085 adenosine metabolic process IDA
 biological_processGO:0051289 protein homotetramerization ISO
 biological_processGO:0051930 regulation of sensory perception of pain ISO
 biological_processGO:0060168 positive regulation of adenosine receptor signaling pathway ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005622 intracellular ISO
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0012506 vesicle membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030175 filopodium IDA
 molecular_functionGO:0003993 acid phosphatase activity ISO
 molecular_functionGO:0008253 5"-nucleotidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity ISS
 molecular_functionGO:0042131 thiamine phosphate phosphatase activity IMP
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0052642 lysophosphatidic acid phosphatase activity ISO


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001167 prostate epithelial hyperplasia "epithelium is multi-layered instead of columnar with increased cell number" [J:63764]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0001168 prostate epithelial dysplasia "abnormal development of the prostate epithelium" [J:63764]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0003177 decreased pain threshold "ordinarily painless stimuli, once perceived, are experienced as being painful" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:81734]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0003998 decreased thermal nociceptive threshold "a lower than average point at which thermal pain sensation is first detectable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0009219 prostate intraepithelial neoplasia "noninvasive prostate duct lesions that affect smaller caliber ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0009220 prostate adenocarcinoma "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

 MP:0009381 abnormal dorsolateral prostate morphology 
Show

Allelic Composition: Pnpla2tm1Rze/Pnpla2tm1Rze
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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