ENSG00000021762


Homo sapiens

Features
Gene ID: ENSG00000021762
  
Biological name :OSBPL5
  
Synonyms : OSBPL5 / oxysterol binding protein like 5 / Q9H0X9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 3087116
Gene end: 3166739
  
Corresponding Affymetrix probe sets: 223464_at (Human Genome U133 Plus 2.0 Array)   233734_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431412
Ensembl peptide - ENSP00000437141
Ensembl peptide - ENSP00000436950
Ensembl peptide - ENSP00000435812
Ensembl peptide - ENSP00000434265
Ensembl peptide - ENSP00000433754
Ensembl peptide - ENSP00000433342
Ensembl peptide - ENSP00000433222
Ensembl peptide - ENSP00000432507
Ensembl peptide - ENSP00000263650
Ensembl peptide - ENSP00000302872
Ensembl peptide - ENSP00000374639
NCBI entrez gene - 114879     See in Manteia.
OMIM - 606733
RefSeq - XM_017017164
RefSeq - NM_001144063
RefSeq - NM_020896
RefSeq - NM_145638
RefSeq - XM_011519873
RefSeq - XM_017017163
RefSeq Peptide - NP_065947
RefSeq Peptide - NP_663613
RefSeq Peptide - NP_001137535
swissprot - E9PRA9
swissprot - E9PPQ2
swissprot - E9PNH0
swissprot - E9PLN3
swissprot - E9PJE6
swissprot - E9PQB4
swissprot - E9PIJ6
swissprot - H0YCD7
swissprot - Q9H0X9
Ensembl - ENSG00000021762
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 osbpl5ENSDARG00000076002Danio rerio
 OSBPL5ENSGALG00000006401Gallus gallus
 Osbpl5ENSMUSG00000037606Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSBPL8 / Q9BZF1 / oxysterol binding protein like 8ENSG0000009103954
Q9BXB5 / OSBPL10 / oxysterol binding protein like 10ENSG0000014464521
OSBPL9 / Q96SU4 / oxysterol binding protein like 9ENSG0000011785920
Q9BXB4 / OSBPL11 / oxysterol binding protein like 11ENSG0000014490920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006893 Golgi to plasma membrane transport NAS
 biological_processGO:0008203 cholesterol metabolic process NAS
 biological_processGO:0015914 phospholipid transport IDA
 biological_processGO:0030301 cholesterol transport NAS
 biological_processGO:0036150 phosphatidylserine acyl-chain remodeling TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005548 phospholipid transporter activity TAS
 molecular_functionGO:0008142 oxysterol binding NAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PS


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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