ENSG00000035687


Homo sapiens

Features
Gene ID: ENSG00000035687
  
Biological name :ADSS
  
Synonyms : adenylosuccinate synthase / ADSS / P30520
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q44
Gene start: 244408494
Gene end: 244452134
  
Corresponding Affymetrix probe sets: 221761_at (Human Genome U133 Plus 2.0 Array)   227310_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355493
NCBI entrez gene - 159     See in Manteia.
OMIM - 103060
RefSeq - XM_011544108
RefSeq - NM_001126
RefSeq Peptide - NP_001117
swissprot - P30520
swissprot - A0A024R5Q7
Ensembl - ENSG00000035687
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adssENSDARG00000002071Danio rerio
 ADSSENSGALG00000010702Gallus gallus
 AdssENSMUSG00000015961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADSSL1 / Q8N142 / adenylosuccinate synthase like 1ENSG0000018510070


Protein motifs (from Interpro)
Interpro ID Name
 IPR001114  Adenylosuccinate synthetase
 IPR018220  Adenylosuccinate synthase, GTP-binding site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027529  Adenylosuccinate synthetase isozyme 2, chordates
 IPR033128  Adenylosuccinate synthase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process NAS
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006167 AMP biosynthetic process NAS
 biological_processGO:0006531 aspartate metabolic process IEA
 biological_processGO:0009168 purine ribonucleoside monophosphate biosynthetic process TAS
 biological_processGO:0014074 response to purine-containing compound IEA
 biological_processGO:0044208 "de novo" AMP biosynthetic process IBA
 biological_processGO:0046040 IMP metabolic process IBA
 biological_processGO:0060359 response to ammonium ion IEA
 biological_processGO:0071257 cellular response to electrical stimulus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004019 adenylosuccinate synthase activity EXP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding NAS
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042301 phosphate ion binding NAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000035687 ADSS / P30520 / adenylosuccinate synthase  / complex






 

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