ENSG00000035720


Homo sapiens

Features
Gene ID: ENSG00000035720
  
Biological name :STAP1
  
Synonyms : Q9ULZ2 / signal transducing adaptor family member 1 / STAP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q13.2
Gene start: 67558728
Gene end: 67607337
  
Corresponding Affymetrix probe sets: 1554343_a_at (Human Genome U133 Plus 2.0 Array)   220059_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379527
Ensembl peptide - ENSP00000265404
NCBI entrez gene - 26228     See in Manteia.
OMIM - 604298
RefSeq - NM_001317769
RefSeq - NM_012108
RefSeq Peptide - NP_001304698
RefSeq Peptide - NP_036240
swissprot - Q9ULZ2
swissprot - A0A024RD91
Ensembl - ENSG00000035720
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STAP1ENSGALG00000011684Gallus gallus
 Stap1ENSMUSG00000029254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAP2 / Q9UGK3 / signal transducing adaptor family member 2ENSG0000017807833


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035877  STAP1, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISS
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0010760 negative regulation of macrophage chemotaxis ISS
 biological_processGO:0042326 negative regulation of phosphorylation ISS
 biological_processGO:0050861 positive regulation of B cell receptor signaling pathway IDA
 biological_processGO:0060100 positive regulation of phagocytosis, engulfment ISS
 biological_processGO:0071222 cellular response to lipopolysaccharide ISS
 biological_processGO:1900028 negative regulation of ruffle assembly ISS
 biological_processGO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway ISS
 biological_processGO:1903980 positive regulation of microglial cell activation ISS
 biological_processGO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity IDA
 biological_processGO:1904140 negative regulation of microglial cell migration IEA
 biological_processGO:1904151 positive regulation of microglial cell mediated cytotoxicity ISS
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0001784 phosphotyrosine residue binding IPI
 molecular_functionGO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity ISS
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IPI
 molecular_functionGO:0005157 macrophage colony-stimulating factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding NAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr