ENSG00000178078


Homo sapiens

Features
Gene ID: ENSG00000178078
  
Biological name :STAP2
  
Synonyms : Q9UGK3 / signal transducing adaptor family member 2 / STAP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 4324043
Gene end: 4342786
  
Corresponding Affymetrix probe sets: 221610_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472851
Ensembl peptide - ENSP00000471052
Ensembl peptide - ENSP00000471281
Ensembl peptide - ENSP00000468927
Ensembl peptide - ENSP00000469657
Ensembl peptide - ENSP00000470321
NCBI entrez gene - 55620     See in Manteia.
OMIM - 607881
RefSeq - XM_011528123
RefSeq - NM_001013841
RefSeq - NM_017720
RefSeq Peptide - NP_001013863
RefSeq Peptide - NP_060190
swissprot - M0QY82
swissprot - M0R2W4
swissprot - M0R0J5
swissprot - M0QZ60
swissprot - Q9UGK3
Ensembl - ENSG00000178078
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stap2aENSDARG00000092810Danio rerio
 stap2bENSDARG00000043281Danio rerio
 Stap2ENSMUSG00000038781Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STAP1 / Q9ULZ2 / signal transducing adaptor family member 1ENSG0000003572021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR011993  PH-like domain superfamily
 IPR035878  STAP2, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
PTK6 Activates STAT3


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101213 PTK6 / Q13882 / protein tyrosine kinase 6  / complex / reaction
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / reaction / complex






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr