ENSMUSG00000038781


Mus musculus

Features
Gene ID: ENSMUSG00000038781
  
Biological name :Stap2
  
Synonyms : Q8R0L1 / Signal-transducing adaptor protein 2 / Stap2
  
Possible biological names infered from orthology : Q9UGK3 / signal transducing adaptor family member 2
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 55997081
Gene end: 56005570
  
Corresponding Affymetrix probe sets: 10451893 (MoGene1.0st)   1424148_a_at (Mouse Genome 430 2.0 Array)   1451261_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038130
NCBI entrez gene - 106766     See in Manteia.
MGI - MGI:2147039
RefSeq - XM_017317201
RefSeq - NM_145934
RefSeq - XM_006523446
RefSeq Peptide - NP_666046
swissprot - Q8R0L1
Ensembl - ENSMUSG00000038781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stap2aENSDARG00000092810Danio rerio
 stap2bENSDARG00000043281Danio rerio
 STAP2ENSG00000178078Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stap1 / Q9JM90 / Signal-transducing adaptor protein 1 / Q9ULZ2* / signal transducing adaptor family member 1*ENSMUSG0000002925425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035878  STAP2, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
PTK6 Activates STAT3


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ctnna1tm1Efu/Ctnna1tm1Efu,Tg(Wap-cre)11738Mam/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000038751 Ptk6 / Q64434 / PTK6 protein tyrosine kinase 6 / Q13882* / protein tyrosine kinase 6*  / reaction / complex
 ENSMUSG00000004040 Stat3 / P42227 / Signal transducer and activator of transcription 3 / P40763*  / reaction / complex






 

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