ENSG00000042286


Homo sapiens

Features
Gene ID: ENSG00000042286
  
Biological name :AIFM2
  
Synonyms : AIFM2 / apoptosis inducing factor, mitochondria associated 2 / Q9BRQ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q22.1
Gene start: 70098223
Gene end: 70132934
  
Corresponding Affymetrix probe sets: 224461_s_at (Human Genome U133 Plus 2.0 Array)   228445_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312370
Ensembl peptide - ENSP00000362345
Ensembl peptide - ENSP00000478931
NCBI entrez gene - 84883     See in Manteia.
OMIM - 605159
RefSeq - NM_001198696
RefSeq - NM_032797
RefSeq Peptide - NP_001185625
RefSeq Peptide - NP_116186
swissprot - Q9BRQ8
Ensembl - ENSG00000042286
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aifm2ENSDARG00000077549Danio rerio
 AIFM2ENSGALG00000004777Gallus gallus
 Aifm2ENSMUSG00000020085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000103  Pyridine nucleotide-disulphide oxidoreductase, class-II
 IPR023753  FAD/NAD(P)-binding domain
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008637 apoptotic mitochondrial changes IDA
 biological_processGO:0022904 respiratory electron transport chain IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005811 lipid droplet IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004174 electron-transferring-flavoprotein dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IDA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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