ENSMUSG00000020085


Mus musculus

Features
Gene ID: ENSMUSG00000020085
  
Biological name :Aifm2
  
Synonyms : Aifm2 / Apoptosis-inducing factor 2 / Q8BUE4
  
Possible biological names infered from orthology : apoptosis inducing factor, mitochondria associated 2 / Q9BRQ8
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B4
Gene start: 61715263
Gene end: 61739260
  
Corresponding Affymetrix probe sets: 10363528 (MoGene1.0st)   1431142_s_at (Mouse Genome 430 2.0 Array)   1431143_x_at (Mouse Genome 430 2.0 Array)   1455112_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070054
Ensembl peptide - ENSMUSP00000078998
Ensembl peptide - ENSMUSP00000097297
Ensembl peptide - ENSMUSP00000101095
NCBI entrez gene - 71361     See in Manteia.
MGI - MGI:1918611
RefSeq - XM_011243572
RefSeq - NM_001039194
RefSeq - NM_001284300
RefSeq - NM_153779
RefSeq - NM_178058
RefSeq - XM_006514122
RefSeq - XM_006514124
RefSeq - XM_006514125
RefSeq - XM_006514126
RefSeq - XM_006514127
RefSeq - XM_006514121
RefSeq Peptide - NP_001271229
RefSeq Peptide - NP_722474
RefSeq Peptide - NP_835159
RefSeq Peptide - NP_001034283
swissprot - Q8BUE4
Ensembl - ENSMUSG00000020085
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aifm2ENSDARG00000077549Danio rerio
 AIFM2ENSGALG00000004777Gallus gallus
 AIFM2ENSG00000042286Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000103  Pyridine nucleotide-disulphide oxidoreductase, class-II
 IPR023753  FAD/NAD(P)-binding domain
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008637 apoptotic mitochondrial changes IEA
 biological_processGO:0022904 respiratory electron transport chain IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0004174 electron-transferring-flavoprotein dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000350 abnormal cell proliferation "anomalous growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Igf2rtm1Wag/Igf2rtm1Wag
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr