ENSG00000050730


Homo sapiens

Features
Gene ID: ENSG00000050730
  
Biological name :TNIP3
  
Synonyms : Q96KP6 / TNFAIP3 interacting protein 3 / TNIP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q27
Gene start: 121131408
Gene end: 121227466
  
Corresponding Affymetrix probe sets: 220655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000057513
Ensembl peptide - ENSP00000424284
Ensembl peptide - ENSP00000426613
Ensembl peptide - ENSP00000427106
NCBI entrez gene - 79931     See in Manteia.
OMIM - 608019
RefSeq - XM_017008625
RefSeq - NM_001128843
RefSeq - NM_001244764
RefSeq - NM_024873
RefSeq - XM_017008620
RefSeq - XM_017008621
RefSeq - XM_017008622
RefSeq - XM_017008623
RefSeq - XM_017008624
RefSeq - XM_011532256
RefSeq - XM_011532257
RefSeq - XM_017008619
RefSeq Peptide - NP_001122315
RefSeq Peptide - NP_001231693
RefSeq Peptide - NP_079149
swissprot - Q96KP6
swissprot - H0Y9J7
Ensembl - ENSG00000050730
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNIP3ENSGALG00000011961Gallus gallus
 Tnip3ENSMUSG00000044162Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNIP1 / Q15025 / TNFAIP3 interacting protein 1ENSG0000014590133


Protein motifs (from Interpro)
Interpro ID Name
 IPR032419  NF-kappa-B essential modulator NEMO, CC2-LZ domain
 IPR033574  TNFAIP3-interacting protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002756 MyD88-independent toll-like receptor signaling pathway IDA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0034142 toll-like receptor 4 signaling pathway IDA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118503 P21580 / TNFAIP3 / TNF alpha induced protein 3  / complex / reaction






 

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