ENSG00000145901


Homo sapiens

Features
Gene ID: ENSG00000145901
  
Biological name :TNIP1
  
Synonyms : Q15025 / TNFAIP3 interacting protein 1 / TNIP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q33.1
Gene start: 151029945
Gene end: 151093577
  
Corresponding Affymetrix probe sets: 207196_s_at (Human Genome U133 Plus 2.0 Array)   243423_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430739
Ensembl peptide - ENSP00000430279
Ensembl peptide - ENSP00000430760
Ensembl peptide - ENSP00000484665
Ensembl peptide - ENSP00000483944
Ensembl peptide - ENSP00000431105
Ensembl peptide - ENSP00000430971
Ensembl peptide - ENSP00000317891
Ensembl peptide - ENSP00000374029
Ensembl peptide - ENSP00000427854
Ensembl peptide - ENSP00000428187
Ensembl peptide - ENSP00000428243
Ensembl peptide - ENSP00000428404
Ensembl peptide - ENSP00000428487
Ensembl peptide - ENSP00000429891
Ensembl peptide - ENSP00000429912
NCBI entrez gene - 10318     See in Manteia.
OMIM - 607714
RefSeq - XM_017008951
RefSeq - NM_001252390
RefSeq - NM_001252391
RefSeq - NM_001252392
RefSeq - NM_001252393
RefSeq - NM_001258454
RefSeq - NM_001258455
RefSeq - NM_001258456
RefSeq - NM_006058
RefSeq - XM_005268355
RefSeq - XM_006714751
RefSeq - XM_006714752
RefSeq - XM_017008945
RefSeq - XM_017008946
RefSeq - XM_017008947
RefSeq - XM_017008948
RefSeq - XM_017008949
RefSeq - XM_017008950
RefSeq - NM_001252385
RefSeq - NM_001252386
RefSeq Peptide - NP_001239315
RefSeq Peptide - NP_001239321
RefSeq Peptide - NP_001239322
RefSeq Peptide - NP_001245383
RefSeq Peptide - NP_001245384
RefSeq Peptide - NP_001245385
RefSeq Peptide - NP_006049
RefSeq Peptide - NP_001239314
RefSeq Peptide - NP_001239319
RefSeq Peptide - NP_001239320
swissprot - E7EW68
swissprot - E7EW15
swissprot - E7EMV7
swissprot - H0YC17
swissprot - A0A0A0MRZ4
swissprot - E7EWG2
swissprot - Q15025
Ensembl - ENSG00000145901
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnip1ENSDARG00000015653Danio rerio
 TNIP1ENSGALG00000004496Gallus gallus
 Tnip1ENSMUSG00000020400Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNIP3 / Q96KP6 / TNFAIP3 interacting protein 3ENSG0000005073019


Protein motifs (from Interpro)
Interpro ID Name
 IPR032419  NF-kappa-B essential modulator NEMO, CC2-LZ domain
 IPR033372  TNFAIP3-interacting protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway ISS
 biological_processGO:0006412 translation TAS
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007159 leukocyte cell-cell adhesion IMP
 biological_processGO:0009101 glycoprotein biosynthetic process IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0045071 negative regulation of viral genome replication TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0050729 positive regulation of inflammatory response ISS
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IBA
 biological_processGO:0085032 modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade IDA
 biological_processGO:1903003 positive regulation of protein deubiquitination IDA
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051019 mitogen-activated protein kinase binding IDA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118503 P21580 / TNFAIP3 / TNF alpha induced protein 3  / reaction / complex






 

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