ENSG00000054118


Homo sapiens

Features
Gene ID: ENSG00000054118
  
Biological name :THRAP3
  
Synonyms : Q9Y2W1 / THRAP3 / thyroid hormone receptor associated protein 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.3
Gene start: 36224416
Gene end: 36305357
  
Corresponding Affymetrix probe sets: 217847_s_at (Human Genome U133 Plus 2.0 Array)   222439_s_at (Human Genome U133 Plus 2.0 Array)   222440_s_at (Human Genome U133 Plus 2.0 Array)   242163_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433825
Ensembl peptide - ENSP00000346634
Ensembl peptide - ENSP00000433066
NCBI entrez gene - 9967     See in Manteia.
OMIM - 603809
RefSeq - XM_005271371
RefSeq - NM_001321471
RefSeq - NM_001321473
RefSeq - NM_005119
RefSeq Peptide - NP_001308400
RefSeq Peptide - NP_001308402
RefSeq Peptide - NP_005110
swissprot - Q9Y2W1
swissprot - E9PML1
Ensembl - ENSG00000054118
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thrap3aENSDARG00000101989Danio rerio
 thrap3bENSDARG00000098228Danio rerio
 THRAP3ENSGALG00000002144Gallus gallus
 Q569Z6ENSMUSG00000043962Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCLAF1 / Q9NYF8 / BCL2 associated transcription factor 1ENSG0000002936340
A2AJT9 / BCLAF3 / BCLAF1 and THRAP3 family member 3ENSG0000017368116


Protein motifs (from Interpro)
Interpro ID Name
 IPR026667  Thyroid hormone receptor-associated protein 3
 IPR029199  THRAP3/BCLAF1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IDA
 biological_processGO:0030521 androgen receptor signaling pathway IDA
 biological_processGO:0042753 positive regulation of circadian rhythm IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IMP
 biological_processGO:0048255 mRNA stabilization IMP
 biological_processGO:0048511 rhythmic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016592 mediator complex IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0035145 exon-exon junction complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding ISS
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity NAS
 molecular_functionGO:0042809 vitamin D receptor binding NAS
 molecular_functionGO:0046966 thyroid hormone receptor binding IDA
 molecular_functionGO:0051219 phosphoprotein binding IDA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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