ENSG00000054148


Homo sapiens

Features
Gene ID: ENSG00000054148
  
Biological name :PHPT1
  
Synonyms : phosphohistidine phosphatase 1 / PHPT1 / Q9NRX4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.3
Gene start: 136848724
Gene end: 136851027
  
Corresponding Affymetrix probe sets: 223207_x_at (Human Genome U133 Plus 2.0 Array)   225683_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000247665
Ensembl peptide - ENSP00000360724
NCBI entrez gene - 29085     See in Manteia.
OMIM - 610167
RefSeq - NM_014172
RefSeq - NM_001135861
RefSeq - NM_001287342
RefSeq - NM_001287343
RefSeq Peptide - NP_001129333
RefSeq Peptide - NP_001274271
RefSeq Peptide - NP_001274272
RefSeq Peptide - NP_054891
swissprot - Q9NRX4
swissprot - V9HWC4
Ensembl - ENSG00000054148
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phpt1ENSDARG00000045567Danio rerio
 PHPT1ENSGALG00000039061Gallus gallus
 Phpt1ENSMUSG00000036504Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007702  Janus
 IPR028441  14kDa phosphohistidine phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0035971 peptidyl-histidine dephosphorylation IDA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IMP
 biological_processGO:0051350 negative regulation of lyase activity IDA
 biological_processGO:2000147 positive regulation of cell motility IEA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IMP
 biological_processGO:2000984 negative regulation of ATP citrate synthase activity IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IDA
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0101006 protein histidine phosphatase activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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