ENSMUSG00000036504


Mus musculus

Features
Gene ID: ENSMUSG00000036504
  
Biological name :Phpt1
  
Synonyms : 14 kDa phosphohistidine phosphatase / Phpt1 / Q9DAK9
  
Possible biological names infered from orthology : phosphohistidine phosphatase 1 / Q9NRX4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 25573430
Gene end: 25575224
  
Corresponding Affymetrix probe sets: 10480804 (MoGene1.0st)   1427903_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037417
NCBI entrez gene - 75454     See in Manteia.
MGI - MGI:1922704
RefSeq - NM_029293
RefSeq Peptide - NP_083569
swissprot - Q9DAK9
Ensembl - ENSMUSG00000036504
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phpt1ENSDARG00000045567Danio rerio
 PHPT1ENSGALG00000039061Gallus gallus
 PHPT1ENSG00000054148Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007702  Janus
 IPR028441  14kDa phosphohistidine phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0035971 peptidyl-histidine dephosphorylation ISO
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IEA
 biological_processGO:0051350 negative regulation of lyase activity IEA
 biological_processGO:2000147 positive regulation of cell motility IEA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IEA
 biological_processGO:2000984 negative regulation of ATP citrate synthase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0101006 protein histidine phosphatase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Pfn1tm1a(EUCOMM)Wtsi/Pfn1+
Genetic Background: B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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