ENSG00000058091


Homo sapiens

Features
Gene ID: ENSG00000058091
  
Biological name :CDK14
  
Synonyms : CDK14 / cyclin dependent kinase 14 / O94921
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q21.13
Gene start: 90466424
Gene end: 91210590
  
Corresponding Affymetrix probe sets: 204604_at (Human Genome U133 Plus 2.0 Array)   211502_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398936
Ensembl peptide - ENSP00000394570
Ensembl peptide - ENSP00000401603
Ensembl peptide - ENSP00000410770
Ensembl peptide - ENSP00000406848
Ensembl peptide - ENSP00000265741
Ensembl peptide - ENSP00000369390
Ensembl peptide - ENSP00000385034
Ensembl peptide - ENSP00000387794
Ensembl peptide - ENSP00000393616
NCBI entrez gene - 5218     See in Manteia.
OMIM - 610679
RefSeq - XM_017012322
RefSeq - NM_001287136
RefSeq - NM_001287137
RefSeq - NM_012395
RefSeq - XM_005250436
RefSeq - XM_005250438
RefSeq - XM_005250439
RefSeq - XM_011516306
RefSeq - XM_017012320
RefSeq - XM_017012321
RefSeq - NM_001287135
RefSeq Peptide - NP_001274065
RefSeq Peptide - NP_001274066
RefSeq Peptide - NP_036527
RefSeq Peptide - NP_001274064
swissprot - E7EUK8
swissprot - O94921
swissprot - C9JWL6
swissprot - F8WF96
swissprot - C9IYJ9
Ensembl - ENSG00000058091
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk14ENSDARG00000074665Danio rerio
 CDK14ENSGALG00000009062Gallus gallus
 Cdk14ENSMUSG00000028926Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK15 / Q96Q40 / cyclin dependent kinase 15ENSG0000013839552
CDK17 / Q00537 / cyclin dependent kinase 17ENSG0000005975846
CDK16 / Q00536 / cyclin dependent kinase 16ENSG0000010222546
CDK18 / Q07002 / cyclin dependent kinase 18ENSG0000011726645


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IDA
 cellular_componentGO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030332 cyclin binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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